ArticleeLife2022
Development of visual cortex in human neonates is selectively modified by postnatal experience.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- White matter structure-function coupling in neonatal brain and its association with Autism-related traits in early childhood.Translational psychiatry · 2026Article
- Dynamics of infant white matter maturation from birth to 6 months.Communications biology · 2026Article
- Computationally Probing the Role of Time-Limited Neuronal Plasticity in Early Visual Development.Developmental science · 2026Article
- Dynamic structure-function coupling in macroscale neonatal brain networks.Communications biology · 2025Article
- Functional organization of the human visual system at birth and across late gestation.bioRxiv : the preprint server for biology · 2025Article
- Assessment of resting state structural-functional relationships in perisylvian region during the early weeks after birth.Brain structure & function · 2025Article
- Cortical Morphology and Morphometric Similarity Network Topology Alterations in Preterm Neonates: Insights From an East Asian Cohort.Human brain mapping · 2025Article
- Visual pathway function in adults born preterm with very low birth weight: a two-country birth cohort study.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- Article
- Gray matter based spatial statistics framework in the 1-month brain: insights into gray matter microstructure in infancy.Brain structure & function · 2024Article
- Human white matter myelinates faster in utero than ex utero.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Development of visual cortex in human neonates is selectively modified by postnatal experience.eLife · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experience-dependent cortical plasticity is a pivotal process of human brain development and essential for the formation of most cognitive functions. Although studies found that early visual experience could influence the endogenous development of visual cortex in animals, little is known about such impact on human infants. Using the multimodal MRI data from the developing human connectome project, we characterized the early structural and functional maps in the ventral visual cortex and their development during neonatal period. Particularly, we found that postnatal time selectively modulated the cortical thickness in the ventral visual cortex and the functional circuit between bilateral primary visual cortices. But the cortical myelination and functional connections of the high-order visual cortex developed without significant influence of postnatal time in such an early period. The structure-function analysis further revealed that the postnatal time had a direct influence on the development of homotopic connection in area V1, while gestational time had an indirect effect on it through cortical myelination. These findings were further validated in preterm-born infants who had longer postnatal time but shorter gestational time at birth. In short, these data suggested in human newborns that early postnatal time shaped the structural and functional development of the visual cortex in selective and organized patterns.
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