ArticleAmerican journal of translational research2022
Clinical value of bedside ultrasound measurements of inferior vena cava diameter and its rate of change in early fluid resuscitation in patients with severe traumatic brain injury.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo explore the clinical value of inferior vena cava diameter (IVCD) detection in guiding early fluid resuscitation in patients with severe traumatic brain injury (sTBI).
methodsEighty patients with sTBI admitted to our hospital from October 2018 to October 2021 were retrospectively enrolled and divided into an observation group (n=40) and control group (n=40) according to the different monitoring methods used for treatment. The cerebrospinal fluid (CSF) lactate level, coagulation function, neurological function, and functional impairment, organ, cognitive, living ability and physical condition, Glasgow score, and adverse reactions in two groups were compared.
resultsThe differences in CSF lactate level and serum levels of PT, APTT and TT between both groups before resuscitation were not significant (all P>0.05). After resuscitation, all these indexes decreased in both groups, so that patients in the observation group had significantly lower CSF lactate level and serum levels of PT, APTT and TT than those in the control group (all P<0.05). Differences in the levels of neurological function factors such as GFAP, NSE, MBP, and S-100B and the scores of NIHSS, SOFA, MMSE, APACHE II and Barthel were not significant between both groups before treatment (all P>0.05). The levels of neurological function factors, NIHSS, SOFA and APACHE II scores decreased in both groups after treatment (all P<0.05) with lower scores in the observation group than the control group (all P<0.05). The MMSE and Barthel scores increased after treatment, and the scores were significantly higher in the observation group than those in the control group (all P<0.05). The GOS scores of patients in the observation group were higher than those in the control group at 1 month after treatment. The incidence of adverse reactions in the observation group (10%) was significantly lower than in the control group (30%).
conclusionMonitoring IVCD to guide fluid resuscitation in patients with sTBI can reduce cerebrospinal fluid lactate levels, better protect patients' vital organs and neurological function, reduce the occurrence of adverse effects, improve patients' quality of life, and improve prognostic outcome.
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36398271PMC9641456W4309412931What OpenQuestion holds
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