Evidence map›Paper›PMID 36398268›Full record

ArticleAmerican journal of translational research2022

Efficacy comparison of restrictive versus massive fluid resuscitation in patients with traumatic hemorrhagic shock.

Xiao Lu, Lan Ying, Haizhen Wang, Libing Jiang, Zhongjun Zheng

Abstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao LuEmergency Department, The Second Affiliated Hospital of Zhejiang University School of Medicine No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang, China.
Lan YingEmergency Department, The Second Affiliated Hospital of Zhejiang University School of Medicine No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang, China.
Haizhen WangEmergency Department, The Second Affiliated Hospital of Zhejiang University School of Medicine No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang, China.
Libing JiangEmergency Department, The Second Affiliated Hospital of Zhejiang University School of Medicine No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang, China.
Zhongjun ZhengEmergency Department, The Second Affiliated Hospital of Zhejiang University School of Medicine No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the therapeutic effect and safety of restrictive versus massive fluid resuscitation in patients with traumatic hemorrhagic shock (TSH).

methodsNinety TSH patients treated in the ICU of the Second Affiliated Hospital of Zhejiang University School of Medicine from June 2020 to January 2021 were recruited for this retrospective study. Among them, 47 cases received restrictive fluid resuscitation (RFR) after admission who were considered as the observation group (OG), while the other 43 cases were given massive fluid resuscitation (MFR) who were treated as the control group (CG). The clinical indices, coagulation function, blood gas analysis, mortality within 72 h, duration of mechanical ventilation, and ICU stay were compared between the two groups, and the amount of resuscitation fluid given and complications that occurred during treatment were recorded. Multivariate logistic regression analysis was used to screen the independent risk factors for complications.

resultsIn comparison to the CG, the resuscitation time, infusion volume, and lactate level in the OG were lower after treatment, while the hemoglobin level and blood gas residual base value (BE) were higher. Besides, the activated partial thromboplastin time (APTT), thrombin time (TT) and prothrombin time (PT) levels and arterial blood carbon dioxide partial pressure (PaCO

conclusionTSH treatment with RFR can effectively accelerate patients' resuscitation with less volume of infusion of resuscitation fluid, reduced time of mechanical ventilation and ICU hospitalization, and promote the recovery of coagulation function. It has good effects and is very suitable for clinical application.

Indexed as

coagulation functionmassive fluid resuscitationRestrictive fluid resuscitationtraumatic hemorrhagic shock

Identifiers

PMID36398268
PMCPMC9641447

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.