Evidence map›Paper›PMID 36398193›Full record

ArticleTransplantation direct2022

Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.

Pranab M Barman, Yuval A Patel, Jiaheng Xie, Min Zhang, Jennifer Jo, Jasmine Sinha, Adeline Answine, Aaron Schluger, Kara Walter, Scott W Biggins and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplantation direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Pranab M BarmanDivision of Gastroenterology, University of California, San Diego, CA.
Yuval A PatelDivision of Gastroenterology, Duke University, Durham, NC.
Jiaheng XieBiostatistics, University of Michigan School of Public Health, Ann Arbor, MI.
Min ZhangBiostatistics, University of Michigan School of Public Health, Ann Arbor, MI.
Jennifer JoDivision of Gastroenterology, Northwestern University, Chicago, IL.
Jasmine SinhaDivision of Gastroenterology, Northwestern University, Chicago, IL.
Adeline AnswineDepartment of Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI.
Aaron SchlugerDepartment of Medicine, Westchester Medical Center, Valhalla, NY.
Kara WalterDivision of Gastroenterology, University of California, Los Angeles, CA.
Scott W BigginsDivision of Gastroenterology, University of Washington, Seattle, WA.
Giuseppe CullaroDivision of Gastroenterology, University of California, San Francisco, CA.
Randi WongDivision of Gastroenterology, University of California, San Francisco, CA.
Jennifer C LaiDivision of Gastroenterology, University of California, San Francisco, CA.
Lisa B VanWagnerDivision of Gastroenterology, Northwestern University, Chicago, IL.
John MageeDivision of Gastroenterology, University of California, San Francisco, CA.
Elizabeth C VernaDepartment of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, MI.
Pratima SharmaDepartment of Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI.
University of California, San Francisco · USNorthwestern University · USUniversity of Michigan–Ann Arbor · USDuke University · USMichigan Medicine · USUniversity of California, San Diego · USUniversity of Washington · USWestchester Medical Center · US

Funding

The Organoid and Cell Culture CoreP30DK132710 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Robert F. Schwabe · 2022 to 2026
$7.2M
NIDDK NIH HHS P30 DK132710
6 · The paper itself

Abstract

Length of stay (LOS) during index solid organ transplant impacts morbidity and healthcare costs. To date, there are no studies evaluating characteristics and outcomes of simultaneous liver-kidney transplant (SLKT) index hospitalization. We examined factors associated with LOS and mortality during index SLKT admission. Methods: Adult SLKT recipients between 2002 and 2017 at 6 transplant centers across 6 UNOS regions were retrospectively enrolled in the US-Multicenter SLKT Consortium. Multivariable regression analyses assessed predictors of SLKT LOS and death during index admission. Results: Median age of cohort (N = 570) was 58 y (interquartile range: 51-64); 63% male, 75% White, 32.3% hepatitis C, 23.3% alcohol-related, 20.1% nonalcoholic steatohepatitis with median MELD-Na at SLKT 28 (23-34). Seventy-one percent were hospitalized at the time of SLKT with median LOS pretransplant of 10 d. Majority of patients were discharged alive (N = 549; 96%)' and 36% were discharged to subacute rehab facility. LOS for index SLKT was 19 d (Q1: 10, Q3: 34 d). Female sex ( Conclusions: Despite excellent survival, index SLKT admission was associated with high-resource utilization with more than half the patients with LOS >2 wk and affected overall patient survival. Further investigation is needed to optimize healthcare resources for these patients in a financially strained healthcare landscape.

Identifiers

PMID36398193
PMCPMC9666195
OpenAlexW4308944220

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.