Evidence map›Paper›PMID 36398114›Full record

Trial reportJBMR plus2022

Low-Intensity Vibration Protects the Weight-Bearing Skeleton and Suppresses Fracture Incidence in Boys With Duchenne Muscular Dystrophy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Maria Luisa Bianchi, Silvia Vai, Giovanni Baranello, Francesca Broggi, Stefan Judex, Thomas Hangartner, Clinton Rubin

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in JBMR plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Prevalence and risk factors of bone fragility in duchenne muscular dystrophy: A systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  3. SIRT1 and exercise-induced bone metabolism: a regulatory nexus.Frontiers in cell and developmental biology · 2025
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Maria Luisa BianchiExperimental Laboratory for Children's Bone Metabolism Research Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS Milan Italy.
Silvia VaiExperimental Laboratory for Children's Bone Metabolism Research Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS Milan Italy.
Giovanni BaranelloUO Neurologia dello Sviluppo Fondazione IRCCS Istituto Neurologico Carlo Besta Milan Italy.
Francesca BroggiExperimental Laboratory for Children's Bone Metabolism Research Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS Milan Italy.
Stefan JudexDepartment of Biomedical Engineering Stony Brook University Stony Brook NY USA.
Thomas HangartnerDepartment of Biomedical, Industrial & Human Factors Engineering BioMedical Imaging Laboratory, Wright State University Dayton OH USA.
Clinton RubinDepartment of Biomedical Engineering Stony Brook University Stony Brook NY USA.ORCID https://orcid.org/0000-0003-0909-7999
IRCCS Istituto Auxologico Italiano · ITStony Brook University · USUCL Biomedical Research Centre · GBWright State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of low-intensity vibration (LIV) to combat skeletal decline in Duchenne Muscular Dystrophy (DMD) was evaluated in a randomized controlled trial. Twenty DMD boys were enrolled, all ambulant and treated with glucocorticoids (mean age 7.6, height-adjusted

Indexed as

BIOMECHANICSBONE MINERAL CONTENTBONE MINERAL DENSITYEXERCISEOSTEOPOROSIS

Identifiers

PMID36398114
PMCPMC9664527
OpenAlexW4297198859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.