Evidence map›Paper›PMID 36398076›Full record

ArticleActa clinica Croatica2022

VALIDATION OF THE BRIEF INTERNATIONAL COGNITIVE ASSESSMENT FOR MULTIPLE SCLEROSIS (BICAMS) IN A LARGE COHORT OF RELAPSING-REMITTING MS PATIENTS.

Jelena Drulović, Gordana Tončev, Čongor Nadj, Dragana Obradović, Jevto Eraković, Šarlota Mesaroš, Mirjana Čukić, Dejan Aleksić, Marko Andabaka, Jovana Ivanović and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta clinica Croatica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Selective associations between cognitive practice effects and reactive balance adaptation in multiple sclerosis.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. A review of the validation of the Brief Cognitive Assessment for Multiple Sclerosis in Latin America.Multiple sclerosis journal - experimental, translational and clinical
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jelena DrulovićDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Gordana TončevDepartment of Neurology, Kragujevac Clinical Center, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Čongor NadjDepartment of Neurology, Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Dragana ObradovićDepartment of Neurology, Military Medical Academy, Medical Faculty, Defense University, Belgrade, Serbia.
Jevto ErakovićDepartment of Neurology, Clinical Center of Montenegro, Podgorica, Montenegro.
Šarlota MesarošDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Mirjana ČukićDepartment of Neurology, Clinical Center of Montenegro, Podgorica, Montenegro.
Dejan AleksićDepartment of Neurology, Kragujevac Clinical Center, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Marko AndabakaInstitute of Genetics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Jovana IvanovićDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Aleksa JovanovićInstitute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Marina KostićDepartment of Neurology, Military Medical Academy, Medical Faculty, Defense University, Belgrade, Serbia.
Gorica MarićInstitute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Aleksandar MarkovićDepartment of Neurology, Military Medical Academy, Medical Faculty, Defense University, Belgrade, Serbia.
Vanja MartinovićDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Aleksandra ParojčićDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Stojan PerićDepartment of CNS Immune-Mediated Disorders, Department of Neurology, University Clinical Center of Serbia, Belgrade, Serbia.
Lorand SakalašDepartment of Neurology, Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Vesna SuknjajaDepartment of Neurology, Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Katarina VesićDepartment of Neurology, Kragujevac Clinical Center, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Sofija VojvodićDepartment of Neurology, Military Medical Academy, Medical Faculty, Defense University, Belgrade, Serbia.
Tijana VukovićDepartment of Neurology, Clinical Center of Montenegro, Podgorica, Montenegro.
Ralph H B BenedictDepartment of Neurology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
Tatjana PekmezovićInstitute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment is one of the most frequently reported symptoms in persons with multiple sclerosis (MS). The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been recommended as a standardized international screening and monitoring tool for brief cognitive assessment. The aim of our study was to assess the reliability and validity of the Serbian version of the BICAMS. A total of 500 relapsing-remitting MS (RRMS) patients and 69 age-, gender- and education-matched healthy control (HC) subjects were examined. All participants performed the BICAMS test battery, which includes the oral version of the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test second edition (CVLT-II), and Brief Visuospatial Memory Test Revised (BVMTR). A randomly selected subset of patients were retested one to three weeks after baseline. Statistically significant differences between patients and HCs were evident on the SDMT and BVMTR (p<0.001). HCs had higher CVLT-II scores but this difference did not reach statistical significance (p=0.063). Cognitive impairment, defined as an abnormal test score on ≥1 subtest, was found in 62.9% of MS patients. There were statistically significant correlations between BICAMS scores and age, education, EDSS and disease duration in patient sample. Test-retest reliability was confirmed with Pearson correlation coefficient of 0.70 in all measures. This study supported the reliability and validity of the Serbian BICAMS, although the CVLT-II version tested here lacked sensitivity to detect MS compared to healthy volunteers.

Indexed as

Multiple SclerosisCognitionCohort StudiesHumansNeuropsychological TestsReproducibility of ResultsBICAMSCognitionCognitive impairmentMultiple sclerosisValidation

Identifiers

PMID36398076
PMCPMC9616040

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.