Evidence map›Paper›PMID 36397834›Full record

ArticleChemistry of materials : a publication of the American Chemical Society2022

Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks.

Meerit Y Said, Christine S Kang, Shunzhi Wang, William Sheffler, Patrick J Salveson, Asim K Bera, Alex Kang, Hannah Nguyen, Ryanne Ballard, Xinting Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Meerit Y SaidInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.ORCID https://orcid.org/0000-0002-3150-3140
Christine S KangInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Shunzhi WangInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
William ShefflerInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Patrick J SalvesonInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.ORCID https://orcid.org/0000-0003-0962-6010
Asim K BeraInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Alex KangInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Hannah NguyenInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Ryanne BallardInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Xinting LiInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Hua BaiInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.ORCID https://orcid.org/0000-0002-0448-4052
Lance StewartInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
Paul LevineInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.
David BakerInstitute for Protein Design, University of Washington, 4000 15th Avenue NE, Seattle, Washington 98195, United States.

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI Nozomi Ando, J Christopher Fromme · 2018 to 2026
$34.2M
NIGMS NIH HHS P30 GM124165
6 · The paper itself

Abstract

Despite remarkable advances in the assembly of highly structured coordination polymers and metal-organic frameworks, the rational design of such materials using more conformationally flexible organic ligands such as peptides remains challenging. In an effort to make the design of such materials fully programmable, we first developed a computational design method for generating metal-mediated 3D frameworks using rigid and symmetric peptide macrocycles with metal-coordinating sidechains. We solved the structures of six crystalline networks involving conformationally constrained 6 to 12 residue cyclic peptides with C2, C3, and S2 internal symmetry and three different types of metals (Zn

Identifiers

PMID36397834
PMCPMC9648172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.