Evidence map›Paper›PMID 36397685›Full record

ArticleAnimal bioscience2023

Role of antioxidants in fertility preservation of sperm - A narrative review.

Ahmad Yar Qamar, Muhammad Ilyas Naveed, Sanan Raza, Xun Fang, Pantu Kumar Roy, Seonggyu Bang, Bereket Molla Tanga, Islam M Saadeldin, Sanghoon Lee, Jongki Cho

Abstract read
In one paragraph

Article in Animal bioscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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  16. Review
  17. Lotus seed (Journal of traditional and complementary medicine · 2025
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmad Yar QamarCollege of Veterinary and Animal Sciences, Jhang 35200, Sub-campus of University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
Muhammad Ilyas NaveedCollege of Veterinary and Animal Sciences, Jhang 35200, Sub-campus of University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
Sanan RazaCollege of Veterinary and Animal Sciences, Jhang 35200, Sub-campus of University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
Xun FangLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Pantu Kumar RoyLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Seonggyu BangLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Bereket Molla TangaLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Islam M SaadeldinLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Sanghoon LeeLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Jongki ChoLaboratory of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

Funding

Ministry of Science and ICTNational Research Foundation of Korea 2021H1D3A2A02040098National Research Foundation of Korea 2021R1A2C2009294National Research Foundation of Korea 2022R1I1A1A01065412
6 · The paper itself

Abstract

Male fertility is affected by multiple endogenous stressors, including reactive oxygen species (ROS), which greatly deteriorate the fertility. However, physiological levels of ROS are required by sperm for the proper accomplishment of different cellular functions including proliferation, maturation, capacitation, acrosomal reaction, and fertilization. Excessive ROS production creates an imbalance between ROS production and neutralization resulting in oxidative stress (OS). OS causes male infertility by impairing sperm functions including reduced motility, deoxyribonucleic acid damage, morphological defects, and enhanced apoptosis. Several in-vivo and in-vitro studies have reported improvement in quality-related parameters of sperm following the use of different natural and synthetic antioxidants. In this review, we focus on the causes of OS, ROS production sources, mechanisms responsible for sperm damage, and the role of antioxidants in preserving sperm fertility.

Indexed as

AntioxidantsInfertilityOxidative StressReactive Oxygen SpeciesSperm

Identifiers

PMID36397685
PMCPMC9996255

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.