ArticleParasites & vectors2022
Systemic veterinary drugs for control of the common bed bug, Cimex lectularius, in poultry farms.
Article in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 21 citations in OpenAlex.
- Influence of hematocrit variation on Cimex lectularius (Hemiptera: Cimicidae) development and reproduction.Journal of medical entomology · 2026Article
- Deployment and transcriptional evaluation of nitisinone, an FDA-approved drug, to control bed bugs.Pest management science · 2025Article
- Repellency and toxicity of long-lasting insecticide-treated bed nets (LLINs) to bed bugs.PloS one · 2025Article
- Bed bugs, Cimex lectularius: Undercover agents in forensic investigations.Journal of forensic sciences · 2025Article
- One Health, many approaches: integrated vector management strategies support One Health goals.Frontiers in insect science · 2025Review
- Repellency of N,N-diethyl-3-methylbenzamide (DEET) during host-seeking behavior of bed bugs (Hemiptera: Cimicidae) in binary choice olfactometer assays.Journal of medical entomology · 2024Article
- Evaluation of the mosquitocidal efficacy of fluralaner, a potential candidate for drug based vector control.Scientific reports · 2024Article
- Pharmacokinetics of intravenously and trans-dermally administered fluralaner in healthy laying shaver hens: fluralaner in chickens.Poultry science · 2024Article
- Detection, Quantification, and Elimination of Wolbachia in Bed Bugs.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Pharmacokinetics of fluralaner as a systemic drug to control infestations of the common bed bug, Cimex lectularius, in poultry facilities.Parasites & vectors · 2023Article
- Fluralaner systemic treatment of chickens results in mortality in Triatoma gerstaeckeri, vector of the agent of Chagas disease.Parasites & vectors · 2023Article
- Behavioral interactions of bed bugs with long-lasting pyrethroid-treated bed nets: challenges for vector control.Parasites & vectors · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe common bed bug, Cimex lectularius L., is a hematophagous ectoparasite that was a common pest in poultry farms through the 1960s. Dichlorodiphenyltrichloroethane (DDT) and organophosphates eradicated most infestations, but concurrent with their global resurgence as human ectoparasites, infestations of bed bugs have been reappearing in poultry farms. Although the impact of bed bugs on chicken health has not been quantified, frequent biting and blood-feeding are expected to cause stress, infections and even anemia in birds. Bed bug control options are limited due to the sensitive nature of the poultry environment, limited products labeled for bed bug control and resistance of bed bug populations to a broad spectrum of active ingredients. Veterinary drugs are commonly used to control endo- and ectoparasites in animals. In this study, we evaluated the effects of two common veterinary drugs on bed bugs by treating the host with systemic antiparasitic drugs.
methodsWe conducted dose-response studies of ivermectin and fluralaner against several bed bug strains using a membrane feeding system. Also, different doses of these drugs were given to chickens and two delivery methods (topical treatment and ingestion) were used to evaluate the efficacy of ivermectin and fluralaner on bed bug mortality.
resultsUsing an artificial feeding system, both ivermectin and fluralaner caused high mortality in insecticide-susceptible bed bugs, and fluralaner was found to be effective on pyrethroid- and fipronil-resistant bed bugs. Ivermectin was ineffective in chickens either by the topical treatment or ingestion, whereas bed bugs that fed on chickens which had ingested fluralaner suffered high mortality when feeding on these chickens for up to 28 days post treatment.
conclusionsThese findings suggest that systemic ectoparasitic drugs have great potential for practical use to control bed bug infestations in poultry farms. These findings also demonstrate the efficacy of fluralaner (and potentially other isoxazolines) as a potent new active ingredient for bed bug control.
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