Evidence map›Paper›PMID 36397077›Full record

ArticleMalaria journal2022

Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?

Bárbara Aparecida Chaves, Denise Anete Madureira de Alvarenga, Matheus de Oliveira Costa Pereira, Marcelo Gordo, Emanuelle L Da Silva, Edson Rodrigues Costa, Aline Souza de Menezes Medeiros, Igor José Martins Pedrosa, Daniela Brito, Maurício Teixeira Lima and 6 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Molecular Screening ofAnimals : an open access journal from MDPI · 2025
    Article
  2. Review
  3. Phylogenetic congruence of Plasmodium spp. and wild ungulate hosts in the Peruvian Amazon.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024
    Article
  4. Monitoring the density of3 Biotech · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Bárbara Aparecida ChavesInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil. bachaves89@gmail.com.
Denise Anete Madureira de AlvarengaGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), Fiocruz, Belo Horizonte, MG, 30190-009, Brazil.
Matheus de Oliveira Costa PereiraGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), Fiocruz, Belo Horizonte, MG, 30190-009, Brazil.
Marcelo GordoLaboratório de Biologia da Conservação, Instituto de Ciências Biológicas, Projeto Sauim-de-Coleira, Universidade Federal do Amazonas, Avenida General Rodrigo Octávio Jordão Ramos, 6200, Coroado, Manaus, AM, 69080-900, Brazil.
Emanuelle L Da SilvaInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Edson Rodrigues CostaInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Aline Souza de Menezes MedeirosInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Igor José Martins PedrosaInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Daniela BritoInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Maurício Teixeira LimaInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Maria Paula MourãoInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Wuelton M MonteiroInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Nikos VasilakisDepartment of Pathology, Center for Biodefense and Emerging Infectious Diseases, Center for Tropical Diseases, Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, 77555, USA.
Cristiana Ferreira Alves de BritoGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), Fiocruz, Belo Horizonte, MG, 30190-009, Brazil.
Gisely C MeloInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Marcus V G LacerdaInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor Heitor, Vieira Dourado, Manaus, AM, 69040-000, Brazil.
Fundação de Medicina Tropical · BRUniversidade do Estado do Amazonas · BRUniversidade Federal do Amazonas · BRThe University of Texas Medical Branch at Galveston · US

Funding

Mechanisms and Public Health Impact of Sylvatic Dengue Virus Emergence in BorneoU01AI115577 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI VASILAKIS, NIKOS · 2016 to 2019
$2.4M
NIAID NIH HHS U01 AI115577
6 · The paper itself

Abstract

backgroundThe groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern.

methodsBoth Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species.

resultsIn this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax.

conclusionThis important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.

Indexed as

MalariaMalaria, VivaxPlasmodiumAnimalsDisease EradicationPlasmodium vivaxMalariaMalaria eliminationNon-human primatesPlasmodium vivaxZoonotic cycle

Identifiers

PMID36397077
PMCPMC9673391
OpenAlexW4309511531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.