Evidence map›Paper›PMID 36397000›Full record

ArticleBMC gastroenterology2022

A risk scoring system for advanced colorectal neoplasia in high-risk participants to improve current colorectal cancer screening in Tianjin, China.

Zhen Yuan, Shuyuan Wang, Zhaoce Liu, Yanfei Liu, Yuqi Wang, Youkui Han, Weifeng Gao, Xinyu Liu, Hongzhou Li, Qinghuai Zhang and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Zhen Yuan *School of Medicine, Nankai University, Tianjin, China.
Shuyuan Wang *School of Medicine, Nankai University, Tianjin, China.
Zhaoce Liu *School of Medicine, Nankai University, Tianjin, China.
Yanfei Liu *School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yuqi WangSchool of Medicine, Nankai University, Tianjin, China.
Youkui HanDepartment of General Surgery, Tianjin Union Medical Center, Tianjin, China.
Weifeng GaoDepartment of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Xinyu LiuTianjin Medical University, Tianjin, China.
Hongzhou LiDepartment of Endoscopy, Tianjin Union Medical Center, Tianjin, China.
Qinghuai ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Hong MaNursing Department, Tianjin Union Medical Center, Tianjin, China.
Junying WangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Xiaomeng WeiHospital Infection Management Division, Tianjin Union Medical Center, Tianjin, China.
Xipeng ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China. xipengzhangtj@163.com.
Wei CuiSchool of Mathematical Sciences and LPMC, Nankai University, Tianjin, China. weicui@nankai.edu.cn.
Chunze ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China. chunze.zhang@nankai.edu.cn.
Nankai University · CNTianjin People's Hospital · CNTianjin Medical University · CNTianjin University of Traditional Chinese Medicine · CNUnion Hospital · CN

Funding

Key R&D Projects in the Tianjin Science and Technology Pillar Program 19YFZCSY00420National key R&D Program of China 2017YFC1700604Natural Science Foundation of Tianjin 21JCZDJC00060Tianjin Hospital Association Hospital Management Research Project 2019ZZ07Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-044A
6 · The paper itself

Abstract

backgroundGiven the limited effectiveness of the current Chinese colorectal cancer (CRC) screening procedure, adherence to colonoscopy remains low. We aim to develop and validate a scoring system based on individuals who were identified as having a high risk in initial CRC screening to achieve more efficient risk stratification and improve adherence to colonoscopy.

methodsA total of 29,504 screening participants with positive High-Risk Factor Questionnaire (HRFQ) or faecal immunochemical test (FIT) who underwent colonoscopy in Tianjin from 2012-2020 were enrolled in this study. Binary regression analysis was used to evaluate the association between risk factors and advanced colorectal neoplasia. Internal validation was also used to assess the performance of the scoring system.

resultsMale sex, older age (age ≥ 50 years), high body mass index (BMI ≥ 28 kg/m

conclusionsOur results showed that the established scoring system could identify very high-risk populations with colorectal neoplasia. Combining this risk score with current Chinese screening methods may improve the effectiveness of CRC screening and adherence to colonoscopy.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerChinaFemaleHumansMaleMiddle AgedRisk FactorsAdvanced colorectal neoplasiaColorectal cancerRisk scoring systemsScreening

Identifiers

PMID36397000
PMCPMC9670427
OpenAlexW4309400191

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.