Evidence map›Paper›PMID 36396903›Full record

ReviewImmunologic research2023

miRNAs as the important regulators of myasthenia gravis: involvement of major cytokines and immune cells.

Marjan Golabi, Zahra Yousefi, Morteza Jafarinia, Mina Montazeri, Sanaz Bastan, Behrooz Ghezelbash, Nahid Eskandari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. The role and mechanism of IL‑35 in myasthenia gravis (Review).International journal of molecular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marjan Golabi *Immunology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra Yousefi *School of Allied Medical Sciences, Shahroud University of Medical Sciences, Shahroud, Iran.
Morteza Jafarinia *Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mina Montazeri *Immunology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Sanaz BastanMedical Laboratory Science Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Behrooz GhezelbashImmunology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Nahid EskandariImmunology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. neskandari@med.mui.ac.ir.ORCID 0000-0003-1910-9359
Isfahan University of Medical Sciences · IRShahroud University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is a type of muscle paralysis created by immune responses against acetylcholine receptor proteins in neuromuscular synapses. This disease is characterized by muscle weakness, especially ocular weakness symptoms that could be ptosis (fall of the upper eyelid) or diplopia (double vision of a single object). Some patients also identified with speech and swallowing problems. The main goals of MG therapeutic approaches are to achieve remission, reduce symptoms, and improve life quality. Recently, other studies have revealed the potential role of various microRNAs (miRNAs) in the development of MG through different mechanisms and have proposed these molecules as effective biomarkers for the treatment of MG. This review was aimed at providing an overview of the critical regulatory roles of various miRNAs in the pathogenesis of this autoimmune disease focusing on human MG studies and the interaction between different miRNAs with important cytokines and immune cells during the development of this autoimmune disease.

Indexed as

MicroRNAsMyasthenia GravisCytokinesHumansReceptors, CholinergicCytokinesMicroRNAsReceptors, CholinergicCytokinesImmune cellsMicroRNAs (miRNAs)Myasthenia gravis

Identifiers

PMID36396903
OpenAlexW4309367876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.