ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023
The Association of Age-Related and Off-Target Retention with Longitudinal Quantification of [
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In one paragraph
Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 19 citations in OpenAlex.
- Tau-PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head-to-head comparison of Flortaucipir and MK6240.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- A Harmonized Visual Reading Framework for Tau PET Staging in Alzheimer Disease.JAMA neurology · 2026Article
- Evaluating early vs. late static SUVR windows of [¹⁸F]MK-6240 tau PET in Alzheimer disease: a head-to-head comparison study.European journal of nuclear medicine and molecular imaging · 2026Article
- Hemispheric lateralization of Tau associations with visual and verbal memory in Alzheimer's disease.European journal of nuclear medicine and molecular imaging · 2026Article
- Visual versus quantitative tau-PET Braak staging in Alzheimer's disease using [European journal of nuclear medicine and molecular imaging · 2026Article
- Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts.Nature aging · 2026Article
- Tau extent outperforms tau load as a predictor of neurodegeneration in Alzheimer's disease.Molecular neurodegeneration · 2026Article
- Off-target binding ofAnnals of nuclear medicine · 2026Article
- Evaluation of [Acta neuropathologica communications · 2026Article
- Cerebellar subregional structural changes across the Alzheimer's disease continuum: a longitudinal analysis of cognitive and behavioural correlates.Brain communications · 2026Article
- Development of Novel PET Tracers for Imaging Non-AD Tauopathies.ACS medicinal chemistry letters · 2025Article
- Review
- Exploring the origins of frequent tau-PET signal in vermal and adjacent regions.European journal of nuclear medicine and molecular imaging · 2025Article
- [Synapse (New York, N.Y.) · 2025Article
- Comparison of visual and analytic methods of Alzheimer's disease pathologic staging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1Journal of medicinal chemistry · 2025Article
- Increased between-network connectivity: A risk factor for tau elevation and disease progression.Neuroscience letters · 2024Article
- Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's disease.Communications biology · 2024Article
- APOE ε4 is associated with decreased synaptic density in cognitively impaired participants.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Evaluating the effect of extra-cerebral off-target binding in [F-18]MK6240 PET scans in early-stage Alzheimer's disease.Imaging neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors at 7 institutions in 4 countries.
Cécile TissotMcGill University, Montreal, Quebec, Canada.
Stijn ServaesMcGill University, Montreal, Quebec, Canada.
Firoza Z LussierDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
João Pedro Ferrari-SouzaDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Joseph TherriaultMcGill University, Montreal, Quebec, Canada.
Pâmela C L FerreiraDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Gleb BezginMcGill University, Montreal, Quebec, Canada.
Bruna BellaverDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Douglas Teixeira LeffaDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Sulantha S MathotaarachchiMcGill University, Montreal, Quebec, Canada.
Mira ChamounMcGill University, Montreal, Quebec, Canada.
Jenna StevensonMcGill University, Montreal, Quebec, Canada.
Nesrine RahmouniMcGill University, Montreal, Quebec, Canada.
Min Su KangArtificial Intelligence and Computational Neurosciences Lab, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Vanessa PallenMcGill University, Montreal, Quebec, Canada.
Nina Margherita-PoltronettiMcGill University, Montreal, Quebec, Canada.
Yi-Ting WangMcGill University, Montreal, Quebec, Canada.
Jaime Fernandez-AriasMcGill University, Montreal, Quebec, Canada.
Andrea L BenedetUniversity of Gothenburg, Gothenburg, Sweden.
Eduardo R ZimmerGraduate Program in Biological Sciences: Biochemistry, Porto Alegre, Brazil.
Jean-Paul SoucyMontreal Neurological Institute, Montreal, Quebec, Canada.
Dana L TudorascuDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Annie D CohenDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Madeleine SharpMontreal Neurological Institute, Montreal, Quebec, Canada.
Serge GauthierMcGill University Research Center for Studies in Aging, Montreal, Quebec, Canada.
Gassan MassarwehDepartment of Radiochemistry, Montreal Neurological Institute, Montreal, Quebec, Canada.
Brian LoprestiDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
William E KlunkDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Suzanne L BakerLawrence Berkeley National Laboratory, Berkeley, California.
Victor L VillemagneDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Pedro Rosa-NetoMcGill University, Montreal, Quebec, Canada.
Tharick A PascoalDepartments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; pascoalt@upmc.edu.
McGill University · CAUniversity of Pittsburgh · USMontreal Neurological Institute and Hospital · CALawrence Berkeley National Laboratory · USSunnybrook Research InstituteUniversidade Federal do Rio Grande do Sul · BRUniversity of Gothenburg · SE
Funding
Longitudinal multicenter head-to-head harmonization of tau PET tracersR01AG073267 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAKER, SUZANNE L, PASCOAL, THARICK · 2021 to 2025
$41.1MHead-to-head comparisons of high-performance plasma phospho-tau epitopes for the detection of Alzheimer's diseaseR01AG075336 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tharick Pascoal · 2022 to 2026
$3.7MNIA NIH HHS R01 AG073267NIA NIH HHS R01 AG075336
Abstract
6-(fluoro-
Indexed as
Alzheimer DiseaseAdultAmyloid beta-PeptidesBrainHumansNeurofibrillary TanglesPositron-Emission Tomographytau ProteinsYoung AdultAmyloid beta-Peptidestau Proteins[18F]MK6240off-target bindingPETreference regiontau
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.