Evidence map›Paper›PMID 36396453›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

A Paden King, Nicholas T Gutsche, Natarajan Raju, Stanley Fayn, Kwamena E Baidoo, Meghan M Bell, Colleen S Olkowski, Rolf E Swenson, Frank I Lin, Samira M Sadowski and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Preclinical characterization of 3p-C-DEPAEJNMMI radiopharmacy and chemistry · 2025
    Article
  8. Preclinical evaluation of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  9. Article
  10. Preclinical safety and effectiveness of a long-acting somatostatin analogue [European journal of nuclear medicine and molecular imaging · 2025
    Article
  11. Review
  12. Chelation of [Dalton transactions (Cambridge, England : 2003) · 2024
    Article
  13. Review
  14. Article
  15. Recent advances in the development ofAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Targeted Alpha Therapy: All We Need to Know aboutPharmaceuticals (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

A Paden KingMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Nicholas T GutscheMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Natarajan RajuChemical and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Stanley FaynMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Kwamena E BaidooMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Meghan M BellMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Colleen S OlkowskiMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Rolf E SwensonChemical and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Frank I LinMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Samira M SadowskiSurgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Stephen S AdlerClinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
Nikki A ThieleChemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee.
Justin J WilsonDepartment of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York; and.
Peter L ChoykeMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Freddy E EscorciaMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; freddy.escorcia@nih.gov.
National Cancer Institute · USCenter for Cancer Research · USNational Institutes of Health · USCornell University · USFrederick National Laboratory for Cancer Research · USNational Heart Lung and Blood Institute · USOak Ridge National Laboratory · US

Funding

Targeted Therapy in Neuroendocrine CancerZIABC011899 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SADOWSKI, SAMIRA · 2019 to 2025
$10.0M
Chelation strategies for s-, p-, and f-block radionuclides for targeted alpha therapyR01EB029259 · NIBIB · CORNELL UNIVERSITY · PI WILSON, JUSTIN J · 2020 to 2023
$1.4M
Expanding the Therapeutic Potential of the Alpha Emitter Radium-223R21EB027282 · NIBIB · CORNELL UNIVERSITY · PI WILSON, JUSTIN J · 2019 to 2021
$619k
NIBIB NIH HHS R01 EB029259NIBIB NIH HHS R21 EB027282
6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) express somatostatin receptors (SSTRs) 2 and 5. Modified variants of somatostatin, the cognate ligand for SSTR2 and SSTR5, are used in treatment for metastatic and locoregional disease. Peptide receptor radionuclide therapy with

Indexed as

Neuroendocrine TumorsOrganometallic CompoundsAnimalsMiceOctreotideRadioisotopesRadiopharmaceuticalsReceptors, SomatostatinSomatostatinTissue DistributionOctreotideOrganometallic CompoundsRadioisotopesRadiopharmaceuticalsReceptors, SomatostatinSomatostatinactiniumneuroendocrine tumorsoctreotateoncologysomatostatintargeted α-therapy

Identifiers

PMID36396453
PMCPMC10071783
OpenAlexW4309365194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.