ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023
The Neural Signature of Impaired Inhibitory Control in Individuals with Heroin Use Disorder.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The resting-state brain activity signatures for addictive disorders.Med (New York, N.Y.) · 2024Pooled it
- Peer-guided movie neurofeedback to facilitate recovery in opioid use disorder.medRxiv : the preprint server for health sciences · 2026Article
- Model-based analysis of stop-signal data reveals robust neural and clinical correlates of evidence accumulation but not inhibition.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- The Phase-Amplitude Coupling Induced by Drug Cues in Individuals With Methamphetamine Use Disorder During Withdrawal.Brain and behavior · 2026Article
- The Impaired Response Inhibition and Salience Attribution Model of Drug Addiction: Recent Neuroimaging Evidence and Future Directions.Annual review of psychology · 2026Review
- Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction.Brain : a journal of neurology · 2025Article
- Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex.BMC psychiatry · 2025Article
- Commonalities and differences in trait-like, risky, and utilitarian decision-making styles between abstinent heroin-dependent individuals and their siblings.Frontiers in psychiatry · 2025Article
- Similarities and Differences in Psychology.Advances in experimental medicine and biology · 2025Review
- Similarities and Differences in Neuroimaging.Advances in experimental medicine and biology · 2025Review
- Social context and drug cues modulate inhibitory control in cocaine addiction: involvement of the STN evidenced through functional MRI.Molecular psychiatry · 2024Article
- Pump the brakes: identifying neurobiological targets to enhance inhibitory control in drug addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Medial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder - a longitudinal structural magnetic resonance imaging study.Translational psychiatry · 2024Article
- Opioid modulation of prefrontal cortex cells and circuits.Neuropharmacology · 2024Review
- Naturalistic drug cue reactivity in heroin use disorder: orbitofrontal synchronization as a marker of craving and recovery.medRxiv : the preprint server for health sciences · 2024Article
- Exploring Social Impairment in Those with Opioid Use Disorder: Linking Impulsivity, Childhood Trauma, and the Prefrontal Cortex.Research square · 2024Article
- The Relationships between Effortful Control, Mind Wandering, and Mobile Phone Addiction Based on Network Analysis.Healthcare (Basel, Switzerland) · 2024Article
- The auditory stimulus facilitates memory guidance in distractor suppression in males with substance use disorder.Frontiers in psychology · 2024Article
- Mobile phone short video use negatively impacts attention functions: an EEG study.Frontiers in human neuroscience · 2024Article
- Whole-brain resting-state connectivity underlying impaired inhibitory control during early versus longer-term abstinence in cocaine addiction.Molecular psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Heroin addiction imposes a devastating toll on society, with little known about its neurobiology. Excessive salience attribution to drug over nondrug cues/reinforcers, with concomitant inhibitory control decreases, are common mechanisms underlying drug addiction. Although inhibitory control alterations generally culminate in prefrontal cortex (PFC) hypoactivations across drugs of abuse, patterns in individuals with heroin addiction (iHUDs) remain unknown. We used a stop-signal fMRI task designed to meet recent consensus guidelines in mapping inhibitory control in 41 iHUDs and 24 age- and sex-matched healthy controls (HCs). Despite group similarities in the stop-signal response time (SSRT; the classic inhibitory control measure), compared with HCs, iHUDs exhibited impaired target detection sensitivity (proportion of hits in go vs false alarms in stop trials;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.