Evidence map›Paper›PMID 36394990›Full record

ArticleJournal of anatomy2023

Synchondrosis fusion contributes to the progression of postnatal craniofacial dysmorphology in syndromic craniosynostosis.

Yukiko Hoshino, Masaki Takechi, Mehran Moazen, Miranda Steacy, Daisuke Koyabu, Toshiko Furutera, Youichirou Ninomiya, Takashi Nuri, Erwin Pauws, Sachiko Iseki

Open access · greenAbstract read
In one paragraph

Article in Journal of anatomy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Evolution, conservatism and overlooked homologies of the mammalian skull.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Yukiko HoshinoDepartment of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0003-0933-2557
Masaki TakechiDepartment of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0001-7279-9243
Mehran MoazenDepartment of UCL Mechanical Engineering, University College London, London, UK.ORCID 0000-0002-9951-2975
Miranda SteacyInstitute of Child Health, Great Ormond Street, University College London, London, UK.
Daisuke KoyabuDepartment of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0002-4087-7742
Toshiko FuruteraDepartment of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Youichirou NinomiyaResearch Organization of Information and Systems, National Institute of Informatics, Tokyo, Japan.
Takashi NuriDepartment of Plastic and Reconstructive Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Erwin PauwsInstitute of Child Health, Great Ormond Street, University College London, London, UK.
Sachiko IsekiDepartment of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0001-8448-9410
Tokyo Medical and Dental University · JPGreat Ormond Street Hospital · GBNational Institute of Informatics · JPOsaka University of Pharmaceutical Sciences · JPThe London College · GB

Funding

Department of Health
6 · The paper itself

Abstract

Syndromic craniosynostosis (CS) patients exhibit early, bony fusion of calvarial sutures and cranial synchondroses, resulting in craniofacial dysmorphology. In this study, we chronologically evaluated skull morphology change after abnormal fusion of the sutures and synchondroses in mouse models of syndromic CS for further understanding of the disease. We found fusion of the inter-sphenoid synchondrosis (ISS) in Apert syndrome model mice (Fgfr2

Indexed as

AcrocephalosyndactyliaCraniofacial DysostosisCraniosynostosesAnimalsCranial SuturesMiceReceptor, Fibroblast Growth Factor, Type 2SkullReceptor, Fibroblast Growth Factor, Type 2Apert syndromecoronal suturecraniosynostosisCrouzon syndromegeometric morphometricsinter-sphenoid synchondrosismidfacial hypoplasiaSaethre-Chotzen syndrome

Identifiers

PMID36394990
PMCPMC9919486
OpenAlexW4309202942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.