ArticleJournal of neuro-oncology2022
Correlation of reduced temporal muscle thickness and systemic muscle loss in newly diagnosed glioblastoma patients.
Article in Journal of neuro-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Frailty and postoperative outcomes in brain tumor patients: a systematic review subdivided by tumor etiology.Journal of neuro-oncology · 2023Pooled it
- Temporal Muscle Thickness Is a Prognostic Factor for Neurological Recovery After Surgery for Chronic Subdural Hematoma.Diagnostics (Basel, Switzerland) · 2026Article
- Review
- Does Cachexia Matter for Glioblastoma Multiforme?Cancers · 2026Article
- Temporal muscle measurements as predictor for outcome in a cohort of IDH-wildtype glioblastoma patients.Brain & spine · 2026Article
- Construction and Validation of a Risk Prediction Model Incorporating Temporal Muscle Thickness for Adverse Outcome in Acute Ischemic Stroke Patients.Journal of central nervous system disease · 2026Article
- Association of temporal and masseter muscle thickness with cognitive function and clinical severity in Alzheimer's disease: a retrospective study.Frontiers in neuroscience · 2026Article
- Association between lateral pterygoid muscle index as a predictor for sarcopenia and overall survival in non-small cell lung cancer patients with brain metastasis.BMC pulmonary medicine · 2025Article
- Two-arm study of sarcopenia in geriatric patients with high-grade glial tumors: temporal muscle thickness and prognostic nutritional index.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- IDO2-AhR axis as central regulator of the kynurenine pathway in glioblastoma.Journal of neuro-oncology · 2025Article
- Predictive value of temporal muscle thickness for prognosis in newly diagnosed IDH wild-type glioblastoma patients: evaluated for a Chinese population.European radiology · 2025Article
- Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity.Scientific reports · 2025Article
- The velocity of temporalis muscle wasting in cerebral metastasis is prognostic for poor survival.Frontiers in oncology · 2025Article
- Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage.Journal of cachexia, sarcopenia and muscle · 2024Article
- The relationship between prognosis and temporal muscle thickness in 102 patients with glioblastoma.Scientific reports · 2024Article
- Temporal Muscle Swelling after Clipping Surgery with Frontotemporal Craniotomy Is Associated with Immediate Postcraniotomy Headache.Neurologia medico-chirurgica · 2024Article
- Automated temporalis muscle quantification and growth charts for children through adulthood.Nature communications · 2023Article
- Association of Temporalis Muscle Mass with Early Cognitive Impairment in Older Patients with Acute Ischemic Stroke.Journal of clinical medicine · 2023Article
- Frailty in cerebellar ischemic stroke-The significance of temporal muscle thickness.Frontiers in neurology · 2023Article
- Temporal muscle thickness has no prognostic relevance in patients with high-grade glioma compared to functional scales.Frontiers in oncology · 2023Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeReduced temporal muscle thickness (TMT) has recently been postulated as a prognostic imaging marker and an objective tool to assess patients frailty in glioblastoma. Our aim is to investigate the correlation of TMT and systemic muscle loss to confirm that TMT is an adequate surrogate marker of sarcopenia in newly diagnosed glioblastoma patients.
methodsTMT was assessed on preoperative MR-images and skeletal muscle area (SMA) was assessed at the third lumbar vertebra on preoperative abdominal CT-scans. Previous published TMT sex-specific cut-off values were used to classify patients as 'patient at risk of sarcopenia' or 'patient with normal muscle status'. Correlation between TMT and SMA was assessed using Spearman's rank correlation coefficient.
resultsSixteen percent of the 245 included patients were identified as at risk of sarcopenia. The mean SMA of glioblastoma patients at risk of sarcopenia (124.3 cm
conclusionOur results confirm the use of TMT as a surrogate marker of total body skeletal muscle mass in glioblastoma, especially in frail patients at risk of sarcopenia. TMT can be used to identify patients with muscle loss early in the disease process, which enables the implementation of adequate intervention strategies.
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