Evidence map›Paper›PMID 36394667›Full record

SynthesisArchives of gynecology and obstetrics2023

Expectant management of viable cesarean scar pregnancies: a systematic review.

Paula Vieira de Mello, Rafael Frederico Bruns, Cynthia Fontoura Klas, Larissa Raso Hammes

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of gynecology and obstetrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Paula Vieira de MelloDepartment of Obstetrics and Gynecology, Universidade Federal Do Paraná, Curitiba, Paraná, Brazil. paula.vmello@gmail.com.ORCID http://orcid.org/0000-0001-6423-1260
Rafael Frederico BrunsDepartment of Obstetrics and Gynecology, Universidade Federal Do Paraná, Curitiba, Paraná, Brazil.ORCID http://orcid.org/0000-0002-2788-9001
Cynthia Fontoura KlasObstetrics and Gynecology Residency Program, Hospital de Clínicas do Paraná, Curitiba, Paraná, Brazil.ORCID http://orcid.org/0000-0003-2001-5667
Larissa Raso HammesObstetrics and Gynecology Residency Program, Hospital de Clínicas do Paraná, Curitiba, Paraná, Brazil.ORCID http://orcid.org/0000-0001-5982-4475
Hospital de Clínicas Universidade Federal do Paraná · BRUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCesarean scar pregnancy (CSP) is a potentially life-threatening disease that has been steadily increasing in prevalence. Pregnancy termination is usually recommended given the risk of life-threatening complications. In some cases, patients refuse to terminate viable CSPs, even after counseling. Recent studies report that, even with a high burden of possible complications and maternal morbidity, many CSPs progress to live, close to term births. The aim of this study is to further demonstrate the natural history of viable cesarean scar pregnancies.

methodsWe conducted a systematic review of original studies reporting cases of expectant management of CSPs with positive fetal heartbeats.

resultsAfter selection, 28 studies were included in the review, with a total of 398 cases of CSP, 136 managed expectantly and 117 with positive fetal heartbeat managed expectantly. This study confirmed that the majority of patients experience live births, as 78% of patients selected for expectant management experienced live births at or close to term, with 79% developing morbidly adherent placenta, 55% requiring hysterectomy, and 40% having severe bleeding. DISCUSSION: The optimal management protocol for CSP is still to be defined and more studies are needed to further elucidate this rare but rising disease. Our study provides information on the natural history of untreated CSPs and suggests that termination may not be the only option offered to the patient.

Indexed as

Abortion, InducedPregnancy, EctopicCesarean SectionCicatrixFemaleHumansPregnancyWatchful WaitingCesarean scar pregnancyEctopic pregnancyExpectant managementMorbidly adherent placentaPregnancy termination

Identifiers

PMID36394667
OpenAlexW4309244392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.