Evidence map›Paper›PMID 36394636›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Cancer mortality in Common Mental Disorders: A 10-year retrospective cohort study.

Federico Chierzi, Elisa Stivanello, Muriel Assunta Musti, Vincenza Perlangeli, Paolo Marzaroli, Francesco De Rossi, Paolo Pandolfi, Alessio Saponaro, Luigi Grassi, Martino Belvederi Murri and 3 more

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Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Mental illness and health literacy in people with cancer: the Australian National Health Survey analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  6. Multimorbidity and animal models.Animal models and experimental medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Federico ChierziDepartment of Mental Health and Substance Abuse, Local Health Trust of Bologna, Bologna, Italy.
Elisa StivanelloDepartment of Public Health, Local Health Trust of Bologna, Bologna, Italy.
Muriel Assunta MustiDepartment of Public Health, Local Health Trust of Bologna, Bologna, Italy.
Vincenza PerlangeliDepartment of Public Health, Local Health Trust of Bologna, Bologna, Italy.
Paolo MarzaroliDepartment of Public Health, Local Health Trust of Bologna, Bologna, Italy.
Francesco De RossiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Paolo PandolfiDepartment of Public Health, Local Health Trust of Bologna, Bologna, Italy.
Alessio SaponaroGeneral Directorate of Health and Social Policies, Emilia-Romagna Region, Bologna, Italy.
Luigi GrassiInstitute of Psychiatry, Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Martino Belvederi MurriInstitute of Psychiatry, Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Angelo FiorittiDepartment of Mental Health and Substance Abuse, Local Health Trust of Bologna, Bologna, Italy.
Domenico BerardiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Marco MenchettiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. marco.menchetti3@unibo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIndividuals with Common Mental Disorders (CMDs) may have a higher cancer mortality. The purpose of this study was to examine cancer-related mortality among patients with CMDs and verify which cancer types are predominantly involved.

methodsWe used the Regional Mental Health Registry of the Emilia-Romagna region, in Northern Italy to identify patients aged ≥ 18 years who received an ICD 9-CM diagnosis of CMDs (i.e., depressive and neurotic disorders) over a 10 year period (2008-2017). Information on cause of death was retrieved from the Regional Cause of Death Registry. Comparisons were made with data from the regional population without CMDs.

resultsAmong 101,487 patients suffering from CMDs (55.7% depression; 44.3% neurotic disorders), 3,087 (37.8%) died from neoplasms. The total standardized mortality ratio (SMR) was 1.82 (95% CI 1.78-1.86) while the SMR for all neoplasms was 2.08 (95% CI 2.01-2.16). Individuals of both genders, with both depressive and neurotic disorders had a higher risk of death from almost all cancers compared with the regional population.

conclusionPatients with CMDs have considerably higher cancer mortality risk than the general population. Higher mortality was observed for a broad range of cancers associated with different aetiologies. It is imperative to promote cancer awareness, prevention and treatment for people with CMDs.

Indexed as

Mental DisordersNeoplasmsFemaleHumansMaleMental HealthNeurotic DisordersRetrospective StudiesCancerComorbidityMortalityPhysical illnessPublic mental health

Identifiers

PMID36394636
PMCPMC9922233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.