ArticleEuropean journal of pain (London, England)2023
Extensive sensorimotor training enhances nociceptive cortical responses in healthy individuals.
Article in European journal of pain (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Association Between Interoceptive Accuracy and Pain Perception: Insights From Trained Musicians and Athletes.European journal of pain (London, England) · 2025Article
- The patient musician: a qualitative investigation of professional classical musicians who previously suffered from depression.BMC public health · 2025Article
- The heating rate matters! contact heat evoked potentials in musicians and non-musicians.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Impact of Chronic Pain on Use-Dependent Plasticity: Corticomotor Excitability and Motor Representation in Musicians With and Without Pain.Brain topography · 2024Article
- Extensive sensorimotor training enhances nociceptive cortical responses in healthy individuals.European journal of pain (London, England) · 2023Article
- The relationship between musicianship and pain. Is chronic pain and its management a problem for student musicians only?Frontiers in pain research (Lausanne, Switzerland) · 2023Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProlonged and repeated sensorimotor training is a crucial driver for promoting use-dependent plasticity, but also a main risk factor for developing musculoskeletal pain syndromes, yet the neural underpinnings that link repetitive movements to abnormal pain processing are unknown.
methodsTwenty healthy musicians, one of the best in vivo models to study use-dependent plasticity, and 20 healthy non-musicians were recruited. Perceptual thresholds, reaction times (RTs) and event-related potentials (ERPs) were recorded using nociceptive intra-epidermal and non-nociceptive transcutaneous electrical stimulation.
resultsIn response to comparable stimulus intensities, musicians compared to non-musicians showed larger non-nociceptive N140 (associated with higher activation of regions within the salience network), higher nociceptive N200 ERPs (associated with higher activation of regions within the sensorimotor network) and faster RTs to both stimuli. Non-musicians showed larger non-nociceptive P200 ERP. Notably, a similar P200 component prominently emerged during nociceptive stimulation in non-musicians. Across participants, larger N140 and N200 ERPs were associated with RTs, whereas the amount of daily practice in musicians explained non-nociceptive P200 and nociceptive P300 ERPs.
conclusionsThese novel findings indicate that the mechanisms by which extensive sensorimotor training promotes use-dependent plasticity in multisensory neural structures may also shape the neural signatures of nociceptive processing in healthy individuals. SIGNIFICANCE: Repetitive sensorimotor training may increase the responsiveness of nociceptive evoked potentials. These novel data highlight the importance of repetitive sensorimotor practice as a contributing factor to the interindividual variability of nociceptive-related potentials.
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