ArticleJournal of cachexia, sarcopenia and muscle2023
Impact of sarcopenia and phase angle on mortality of the very elderly.
Article in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between phase angle and the nutritional status in pediatric populations: a systematic review.Frontiers in nutrition · 2023Pooled it
- Lower bioelectrical phase angle is associated with audiometric hearing loss in middle-aged and older adults.GeroScience · 2026Article
- A three-biomarker panel for frailty prediction and risk stratification in institutionalized older adults: a multicenter validation study.European geriatric medicine · 2026Article
- Association of phase angle with malnutrition and sarcopenia in interstitial lung disease: a cross-sectional analysis of body composition and functional decline.BMC pulmonary medicine · 2026Observational
- Dual Roles of CCN5/WISP2 in Cytosol and Secretome for Maintaining Muscle Homeostasis and Preventing Sarcopenia.Journal of cachexia, sarcopenia and muscle · 2026Article
- Phase angle reference values in healthy Chinese adults: A descriptive cross-sectional study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Sarcopenia in amyotrophic lateral sclerosis: a key predictor of respiratory dysfunction and disease progression.Frontiers in nutrition · 2026Article
- Normative reference values of the phase angle for Korean population: an analysis of the Korea National Health and Nutrition Examination Survey.Aging clinical and experimental research · 2025Article
- Sarcopenia as a predictor of mortality in centenarians: insights from a prospective cohort study.BMC geriatrics · 2025Article
- Phase angle as a predictor of motor function decline in children with Duchenne muscular dystrophy.BMC pediatrics · 2025Article
- Article
- New research progress of sarcopenia in surgically resectable malignant tumor diseases.World journal of clinical oncology · 2025Review
- Optimal lumbar vertebral level for trunk muscle CT assessments in opportunistic sarcopenia screening: a cross-sectional study.BMJ open · 2025Article
- Association between phase angle and all-cause mortality in adults aged 18-49 years: NHANES 1999-2004.Scientific reports · 2025Article
- Associations between sarcopenia (defined by low muscle mass), inflammatory markers, and all-cause mortality in older adults: mediation analyses in a large U.S. NHANES community sample, 1999-2006.Frontiers in medicine · 2025Article
- Development and Validation of a Risk Predictive Model for Adverse Postoperative Health Status of Elderly Patients Undergoing Major Abdominal Surgery Using Lasso-Logistic Regression.Clinical interventions in aging · 2025Article
- Quality of Life and non-motor symptoms Improvement in Parkinson's Disease through Nutritional Intervention: a Case Study.Journal of preventive medicine and hygiene · 2024Article
- Limited predictive value of bioelectrical phase angle for the development of sarcopenia in older Europeans.The journal of nutrition, health & aging · 2024Observational
- The association between the change in severity score from baseline and the outcomes of critically ill patients was enhanced by integration of bioimpedance analysis parameters.Scientific reports · 2024Article
- Associations between objectively measured overall and intensity-specific physical activity and phase angle in older adults.Scientific reports · 2024Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundSarcopenia is a major component of geriatric syndrome and associated with poor clinical outcomes and mortality. However, diagnosing sarcopenia in the very elderly is difficult, and data on its epidemiology and devastating effects in this group are scarce. Phase angle (PA) is measured using bioimpedance spectroscopy and known to reflect cellular integrity and health. This study aimed to clarify the impact of sarcopenia and PA on mortality risk in very elderly people living in long-term care facilities.
methodsThis prospective cohort study enrolled elderly residents living in nine long-term care facilities. We collected the participants' data, such as body mass index (BMI), comorbidities and laboratory data, from September to October 2017 and mortality data until October 2019. Nutritional status was evaluated using the Mini Nutritional Assessment (MNA) score, and multifrequency bioimpedance spectroscopy was used to assess body composition including PA. Appendicular skeletal muscle mass was calculated using the body composition monitor-derived equation of Taiwan's researchers. Sarcopenia was diagnosed using the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) definition (sarcopenia vs. normal group). We divided the participants into two groups according to the median PA value of 3.65° (high vs. low group) and performed multivariate regression analyses to verify the association with mortality risk according to sarcopenia diagnosis or PA group.
resultsA total of 279 elderly participants were enrolled; of them, 238 (85.3%) were diagnosed with sarcopenia according to EWGSOP2 guidelines. The median patient age was 83 years, 211 (75.6%) were female and the median BMI was 20.4 kg/m
conclusionsSarcopenia is prevalent among the very elderly patients in long-term care facilities. Sarcopenia and low PA are significantly associated with higher mortality risk.
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