Evidence map›Paper›PMID 36394084›Full record

ArticleOrthopaedic surgery2023

Dynamic Spine Hyperflexion Is Related to Vertebral Compression Fractures in Postmenopausal Women.

Zhirong Zheng, Wenhao Hu, Tian Tian, Weibo Liu, Xiangyu Wang, Meng Gao, Yonggang You, Xuesong Zhang

Open access · goldAbstract read
In one paragraph

Article in Orthopaedic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Zhirong ZhengMedical School of Chinese PLA, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-8535-9968
Wenhao HuThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Tian TianDepartment of Orthopedics, PLA Strategic Support Force Characteristic Medical Center, Beijing, China.
Weibo LiuThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Xiangyu WangThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Meng GaoThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Yonggang YouThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Xuesong ZhangThe Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNCenter for Strategic Research · RU

Funding

Medical big data and artificial intelligence of Chinese PLA General Hospital Foundation 2019MBD-022National Natural Science Foundation of China 81972128
6 · The paper itself

Abstract

objectivePrevious studies on osteoporotic vertebral fractures are usually based on the neutral posture of spine; however, the fractures are usually associated with the flexion posture of spine. Therefore, we aimed to ascertain the relationship between vertebral compression fractures and thoracolumbar hyperflexion Cobb angles (TLHCobb) and determine the clinical cut-off of the TLHCobb angle.

methodsIn this retrospective case-control study, TLHCobbs were collected from 154 postmenopausal women (67.45 ± 6.68 years) with vertebral compression fractures (study group) and 310 postmenopausal women (66.57 ± 8.22 years) without vertebral compression fractures (control group) from June 2017 to July 2019. Demographic data, clinical data, and quantitative computed tomography (QCT) findings were compared between the groups. Chi-squared tests, unpaired t-tests, and Mann Whitney U were used to assess the group characteristics and proportions. Logistic regression was used to examine the association between vertebral compression fractures and TLHCobb. The cut-off of the TLHCobb was determined by ROC curve and Youden's index.

resultsFracture prevalence was higher in the higher TLHCobb study group than that in the control group [OR = 2.81 (2.15-3.67)] after adjusting for age, BMI, and QCT findings. TLHCobbs at and >20.05° were associated with an increased fracture prevalence and ORs of 2.79 (1.82-4.27) and 4.83 (3.24-7.20), respectively. TLHCobb, disk height (semiquantitative grading score) and QCT values differed between the study and control groups (p < 0.001 for all three). There were no significant differences in body mass index (BMI), or coronal TLCobb between the two groups.

conclusionThere was an association between the prevalence of vertebral compression fractures and TLHCobbs in postmenopausal women, and a TLHCobb > 20.05° can be an indicator of vertebral fracture.

Indexed as

Bone Diseases, MetabolicFractures, CompressionOsteoporotic FracturesSpinal FracturesBone DensityCase-Control StudiesFemaleHumansLumbar VertebraePostmenopauseRetrospective Studiesosteoporosispostmenopausal womenthoracolumbar hyperflexionvertebral fracture

Identifiers

PMID36394084
PMCPMC9837278
OpenAlexW4309243231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.