Evidence map›Paper›PMID 36394073›Full record

ArticlePhysiological reports2022

Right ventricular energy metabolism in a porcine model of acute right ventricular pressure overload after weaning from cardiopulmonary bypass.

Masaki Kajimoto, Muhammad Nuri, Justin R Sleasman, Kevin A Charette, Hidemi Kajimoto, Michael A Portman

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Masaki KajimotoCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0001-9377-1354
Muhammad NuriDivision of Cardiothoracic Surgery at Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Justin R SleasmanDivision of Pediatric Cardiac Surgery, Lucile Packard Children's Hospital, Palo Alto, California, USA.
Kevin A CharetteDivision of Pediatric Cardiac Surgery, Seattle Children's Hospital, Seattle, Washington, USA.
Hidemi KajimotoCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Michael A PortmanCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0002-8168-3725
Children's Hospital of Philadelphia · USLucile Packard Children's Hospital · USSeattle Children's Hospital · USUniversity of Washington · US

Funding

Thyroid Regulation in the Developing HeartR01HL060666 · NHLBI · UNIVERSITY OF WASHINGTON · PI PORTMAN, MICHAEL A · 1998 to 2013
$4.7M
NHLBI NIH HHS R01 HL060666
6 · The paper itself

Abstract

Acute right ventricular pressure overload (RVPO) occurs following congenital heart surgery and often results in low cardiac output syndrome. We tested the hypothesis that the RV exhibits limited ability to modify substrate utilization in response to increasing energy requirements during acute RVPO after cardiopulmonary bypass (CPB). We assessed the RV fractional contributions (Fc) of substrates to the citric acid cycle in juvenile pigs exposed to acute RVPO by pulmonary artery banding (PAB) and CPB. Sixteen Yorkshire male pigs (median 38 days old, 12.2 kg of body weight) were randomized to SHAM (Ctrl, n = 5), 2-h CPB (CPB, n = 5) or CPB with PAB (PAB-CPB, n = 6). Carbon-13 (

Indexed as

Ventricular Dysfunction, RightAnimalsCardiopulmonary BypassEnergy MetabolismLactatesMaleSwineVentricular PressureWeaningLactatescardiopulmonary bypasscongenital heart diseasemyocardial metabolismright ventricular pressure overload

Identifiers

PMID36394073
PMCPMC9669618
OpenAlexW4309512075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.