Evidence map›Paper›PMID 36394031›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia

Xiangru Chen, Peiyu Yan, Wenqiang Zhang, Xin He, Rihua Jiang, Yulin Li, Jing Sun, Jinlan Jiang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiangru ChenDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Peiyu YanDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Wenqiang ZhangDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Xin HeDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Rihua JiangDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Yulin LiThe Key Laboratory of Pathobiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun, China.
Jing SunDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Jinlan JiangScientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, China.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgenic alopecia (AGA) is a common disease that negatively affects patients' physical and mental health. AGA can be treated with drugs that improve the perifollicular microenvironment, such as 5α-reductase inhibitors (e.g., dutasteride [DUT]), androgen receptor blockers, and minoxidil. However, the efficacy of these treatments is limited. Therefore, this study aimed to show that nanoparticles are effective as stable carriers with high curative benefits and little adverse effects. The

Indexed as

5α-reductaseandrogenic alopecia therapyandrogen receptordermal papilla cell membrane biomimeticpoly(lactic-co-glycolic acid) nanoparticles

Identifiers

PMID36394031
PMCPMC9644085
OpenAlexW4307552585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.