Evidence map›Paper›PMID 36394015›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Crowding-induced morphological changes in synthetic lipid vesicles determined using smFRET.

Steven D Quinn, Lara Dresser, Sarah Graham, Donato Conteduca, Jack Shepherd, Mark C Leake

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Emerging Designs and Applications for Biomembrane Biosensors.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven D QuinnSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.
Lara DresserSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.
Sarah GrahamSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.
Donato ConteducaSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.
Jack ShepherdSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.
Mark C LeakeSchool of Physics, Engineering and Technology, University of York, York, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid vesicles are valuable mesoscale molecular confinement vessels for studying membrane mechanics and lipid-protein interactions, and they have found utility among bio-inspired technologies, including drug delivery vehicles. While vesicle morphology can be modified by changing the lipid composition and introducing fusion or pore-forming proteins and detergents, the influence of extramembrane crowding on vesicle morphology has remained under-explored owing to a lack of experimental tools capable of capturing morphological changes on the nanoscale. Here, we use biocompatible polymers to simulate molecular crowding

Indexed as

FRETlipid vesiclemembrane mechanicsmolecular crowdingsingle-moleculeTIRF

Identifiers

PMID36394015
PMCPMC9650091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.