Evidence map›Paper›PMID 36389809›Full record

ArticleFrontiers in immunology2022

Immune infiltration in aggressive papillary craniopharyngioma: High infiltration but low action.

Yanfei Jia, Lin Ma, Kefan Cai, Bochao Zhang, Wentao Wu, Youchao Xiao, Ning Qiao, Siming Ru, Lei Cao, Hua Gao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Targeted therapy of papillary craniopharyngioma.Medical oncology (Northwood, London, England) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Inflammatory mediator contributes to leptin resistance and obesity in craniopharyngioma.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yanfei JiaDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Lin MaDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Kefan CaiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Bochao ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wentao WuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Youchao XiaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ning QiaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Siming RuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Lei CaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hua GaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Songbai GuiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Beijing Tian Tan Hospital · CNCapital Medical University · CNLanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary craniopharyngiomas (PCPs) are biologically benign but clinically aggressive lesions hence affect the quality of life. The expression of inflammatory mediators and regulation of the immune microenvironment in PCPs have not been investigated much. In this study, for the first time, we assessed the immune cell infiltration and immune cell signatures in PCPs by analyzing the bulk-RNA sequencing data and immunohistochemical staining. Additionally, we performed qRT-PCR analysis to detect inflammatory mediators interleukin-1α (

Indexed as

CraniopharyngiomaPituitary NeoplasmsHumansInflammation MediatorsInterleukin-6Quality of LifeTumor MicroenvironmentInflammation MediatorsInterleukin-6hypothalamic invasionImmune infiltrationinterleukin-1αinterleukin-6papillary craniopharyngioma

Identifiers

PMID36389809
PMCPMC9664078
OpenAlexW4308007029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.