Evidence map›Paper›PMID 36389760›Full record

ArticleFrontiers in immunology2022

An ambient-temperature stable nanoparticle-based vaccine for nasal application that confers long-lasting immunogenicity to carried antigens.

Adolfo Cruz-Resendiz, Gonzalo Acero, Alicia Sampieri, Goar Gevorkian, Carolina Salvador, Laura Escobar, Margarita Jacaranda Rosendo-Pineda, Mara Medeiros, Luis Vaca

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Adolfo Cruz-ResendizInstituto de Fisiología Celular, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Gonzalo AceroInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Alicia SampieriInstituto de Fisiología Celular, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Goar GevorkianInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Carolina SalvadorDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Laura EscobarDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Margarita Jacaranda Rosendo-PinedaInstituto de Fisiología Celular, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Mara MedeirosNephrology Research Laboratory, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Luis VacaInstituto de Fisiología Celular, Universidad Nacional Autónoma de México. Ciudad Universitaria, Mexico City, Mexico.
Universidad Nacional Autónoma de México · MXHospital Infantil de México Federico Gómez · MXUniversidad Autónoma de la Ciudad de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyhedrins are viral proteins present in a large family of baculoviruses that form occlusion bodies (polyhedra). These structures protect the virus particles from the outside environment until they are ingested by susceptible insects. Occluded viruses can sustain inclement weather for long periods of time. Therefore, the polyhedra is a natural preservative that keeps the viral structure intact at ambient temperature for years. In a previous study we identified the first 110 amino acids from polyhedrin (PH

Indexed as

NanoparticlesVaccinesAntigensGreen Fluorescent ProteinsTemperatureAntigensGreen Fluorescent ProteinsVaccinesbaculovirusnanoparticlesnasal immunizationocclusion bodiespolyhedrin

Identifiers

PMID36389760
PMCPMC9660247
OpenAlexW4307871582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.