Evidence map›Paper›PMID 36389744›Full record

ArticleFrontiers in immunology2022

SARS-CoV-2 tetrameric RBD protein blocks viral infection and induces potent neutralizing antibody response.

Zheng Liu, Chenglu Yang, Haokun Zhang, Guojie Cao, Senzhen Wang, Siwen Yin, Yanming Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zheng LiuLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Chenglu YangLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Haokun ZhangLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Guojie CaoLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Senzhen WangLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Siwen YinLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Yanming WangLaboratory of Epigenetics and Translational Medicine, School of Life Sciences, Henan University, Kaifeng, Henan, China.
Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed serious threats to global health and economy and calls for the development of safe treatments and effective vaccines. The receptor-binding domain in the spike protein (S

Indexed as

Antibodies, NeutralizingCOVID-19Angiotensin-Converting Enzyme 2AnimalsCOVID-19 VaccinesHumansMembrane GlycoproteinsMiceSARS-CoV-2Spike Glycoprotein, CoronavirusViral Envelope ProteinsAngiotensin-Converting Enzyme 2Antibodies, NeutralizingCOVID-19 VaccinesMembrane GlycoproteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Viral Envelope Proteins2xS-RBD-mFchACE2SARS-CoV-2Vaccineviral infection

Identifiers

PMID36389744
PMCPMC9659643
OpenAlexW4307870777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.