Evidence map›Paper›PMID 36389689›Full record

ReviewFrontiers in immunology2022

Dysregulation and chronicity of pathogenic T cell responses in the pre-diseased stage of lupus.

Justus Ohmes, Sara Comdühr, Reza Akbarzadeh, Gabriela Riemekasten, Jens Y Humrich

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  13. Core fucosylation and its roles in gastrointestinal glycoimmunology.World journal of gastrointestinal oncology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Justus OhmesDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
Sara ComdührDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
Reza AkbarzadehDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
Gabriela RiemekastenDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
Jens Y HumrichDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
University of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the normal immune system, T cell activation is tightly regulated and controlled at several levels to ensure that activation occurs in the right context to prevent the development of pathologic conditions such as autoimmunity or other harmful immune responses. CD4

Indexed as

AutoimmunityLupus Erythematosus, SystemicCell DifferentiationHumansLymphocyte ActivationT-Lymphocytes, RegulatoryautoimmunitygeneticsIL-2immune regulationmetabolismsystemic lupus erythematosusT cell signaling

Identifiers

PMID36389689
PMCPMC9650673
OpenAlexW4307927193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.