Evidence map›Paper›PMID 36389679›Full record

ArticleFrontiers in immunology2022

IL-1β promotes IL-9-producing Th cell differentiation in IL-2-limiting conditions through the inhibition of BCL6.

D Alejandro Canaria, Maia G Clare, Bingyu Yan, Charlotte B Campbell, Zachariah A Ismaio, Nicole L Anderson, Sungtae Park, Alexander L Dent, Majid Kazemian, Matthew R Olson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

D Alejandro CanariaDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Maia G ClareDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Bingyu YanDepartment of Biochemistry, Purdue University, West Lafayette, IN, United States.
Charlotte B CampbellDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Zachariah A IsmaioDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Nicole L AndersonDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Sungtae ParkDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Alexander L DentDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States.
Majid KazemianDepartment of Biochemistry, Purdue University, West Lafayette, IN, United States.
Matthew R OlsonDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · USIndiana University – Purdue University Indianapolis · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4M
Joint submission for administrative supplement proposal: HIPAA aligned storage and computing solutionR35GM138283 · NIGMS · PURDUE UNIVERSITY · PI KAZEMIAN, MAJID · 2020 to 2024
$2.0M
NCI NIH HHS P30 CA023168NIGMS NIH HHS R35 GM138283
6 · The paper itself

Abstract

IL-9-producing CD4

Indexed as

Interleukin-4Interleukin-9T-Lymphocytes, Helper-InducerAnimalsCell DifferentiationCytokinesInterleukin-1betaInterleukin-2MiceNF-kappa BProto-Oncogene Proteins c-bcl-6Transforming Growth Factor betaBcl6 protein, mouseCytokinesInterleukin-1betaInterleukin-2Interleukin-4Interleukin-9NF-kappa BProto-Oncogene Proteins c-bcl-6Transforming Growth Factor betaIL-2 signalingIL-9 cytokinenuclear factor-kBTh9 cellsTh cell differentiation

Identifiers

PMID36389679
PMCPMC9663844
OpenAlexW4307832601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.