Evidence map›Paper›PMID 36389386›Full record

ArticleFrontiers in pediatrics2022

Energy cost of walking in obese survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort.

Matthew D Wogksch, Emily R Finch, Vikki G Nolan, Matthew P Smeltzer, Fawaz Mzayek, Chelsea G Goodenough, Ching-Hon Pui, Hiroto Inaba, Daniel A Mulrooney, Sue C Kaste and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Matthew D WogkschDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Emily R FinchDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Vikki G NolanDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, United States.
Matthew P SmeltzerDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, United States.
Fawaz MzayekDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, United States.
Chelsea G GoodenoughDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Ching-Hon PuiDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Hiroto InabaDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Daniel A MulrooneyDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Sue C KasteDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Tara M BrinkmanDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Jennifer Q LanctotDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Deo Kumar SrivastavaDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, United States.
John L JefferiesDivision of Cardiovascular Diseases, Institute for Cardiovascular Science, University of Tennessee Health Science Center, Memphis, TN, United States.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Leslie L RobisonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Melissa M HudsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
Kirsten K NessDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States.
St. Jude Children's Research Hospital · USUniversity of Memphis · USUniversity of Tennessee Health Science Center · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
The St. Jude Lifetime CohortU01CA195547 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HUDSON, MELISSA M, NESS, KIRSTEN KIMBERLIE · 2015 to 2024
$14.9M
Motor Proficiency and Physical Activity in Adult Survivors of Childhood ALLR01CA132901 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI NESS, KIRSTEN KIMBERLIE · 2009 to 2012
$2.6M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA132901NCI NIH HHS U01 CA195547
6 · The paper itself

Abstract

Purpose: Adult survivors of childhood acute lymphoblastic leukemia (ALL) have impaired adaptive physical function and poor health-related quality of life (HRQoL). Obesity may contribute to these impairments by increasing the physiological cost of walking. Due to treatment exposures during ALL therapy, survivors' cost of walking may be more impacted by obesity than the general population. Therefore, we examined associations between obesity, persistent motor neuropathy, and energy cost of walking; and examined associations between energy cost of walking, adaptive physical function, and HRQoL, in adult survivors of childhood ALL vs. community controls. Methods: Obesity was measured Results: Obese individuals (BMI > 40 kg/m Conclusion: Obesity was associated with increased PCI. Survivors with high PCI had disproportionately worse adaptive physical function and HRQoL compared to controls. Survivors with increased energy costs of walking may benefit from weight loss interventions.

Indexed as

acute lymphoblastic leukemiachildhood cancerfitnessobesityquality of life

Identifiers

PMID36389386
PMCPMC9650430
OpenAlexW4307701792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.