Evidence map›Paper›PMID 36389179›Full record

ArticleFrontiers in neural circuits2022

Dissociable effects of oxycodone on behavior, calcium transient activity, and excitability of dorsolateral striatal neurons.

Joshua Barry, Katerina D Oikonomou, Allison Peng, Daniel Yu, Chenyi Yang, Peyman Golshani, Christopher J Evans, Michael S Levine, Carlos Cepeda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neural circuits, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Joshua BarryIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Katerina D OikonomouIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Allison PengIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Daniel YuIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Chenyi YangDepartment of Neurology, University of California, Los Angeles, Los Angeles, CA, United States.
Peyman GolshaniIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Christopher J EvansDepartment of Neurology, University of California, Los Angeles, Los Angeles, CA, United States.
Michael S LevineIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Carlos CepedaIntellectual and Developmental Disabilities Research Center (IDDRC), Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · USIntel (United States) · US

Funding

The Role of Striosome Neurons in Mediating Opiod RewardP50DA005010 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YANG, XIANGDONG WILLIAM · 1987 to 2021
$30.7M
NIDA NIH HHS P50 DA005010
6 · The paper itself

Abstract

Opioids are the most common medications for moderate to severe pain. Unfortunately, they also have addictive properties that have precipitated opioid misuse and the opioid epidemic. In the present study, we examined the effects of acute administration of oxycodone, a μ-opioid receptor (MOR) agonist, on Ca

Indexed as

CalciumOxycodoneAnimalsCorpus StriatumDopamineMiceNeuronsCalciumDopamineOxycodoneCa2+ transientscerebral cortexelectrophysiologylocomotionMiniscopesoxycodonestriatum

Identifiers

PMID36389179
PMCPMC9643681
OpenAlexW4307553638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.