ArticleFrontiers in aging neuroscience2022
Nomogram to predict postoperative cognitive dysfunction in elderly patients undergoing gastrointestinal tumor resection.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review.Nursing open · 2024Pooled it
- Prediction models for postoperative cognitive dysfunction in adults: a systematic review of methodological quality and clinical applicability.Frontiers in neurologyPooled it
- Cognitive Impact of Colorectal Cancer Surgery in Elderly Patients: A Narrative Review.Cancers · 2026Review
- Temporal Dynamic Machine Learning Prediction of Postoperative Gastrointestinal Dysfunction Duration in Esophageal Cancer: Integrating Preoperative and Perioperative Routine Blood Temporal Data and Dynamic Ultrasonic Features.International journal of general medicine · 2026Article
- Developed a knowledge base of risk factors for postoperative cognitive dysfunction: a retrospective database study.Scientific reports · 2025Article
- Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats.Journal of neuroinflammation · 2024Article
- Preoperative mild cognitive impairment as a risk factor of postoperative cognitive dysfunction in elderly patients undergoing spine surgery.Frontiers in aging neuroscience · 2024Article
- Predicative factors and development of a nomogram for postoperative delayed neurocognitive recovery in elderly patients with gastric cancer.Aging clinical and experimental research · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: To establish a nomogram model for the prediction of postoperative cognitive dysfunction (POCD) in elderly patients undergoing gastrointestinal tumor resection. Methods: A total of 369 elderly patients scheduled for elective gastrointestinal tumor resection under general anesthesia were included. The cognitive function of each participant was assessed by the Mini-Mental State Examination (MMSE) 1 day before surgery and 7 days after surgery for the diagnosis of POCD. According to the results, patients were divided into a POCD group and a non-POCD group. The differences in hospitalization data and examination results between the two groups were compared. A logistic regression model was used to explore the risk factors for POCD in elderly patients undergoing gastrointestinal tumor resection, and a nomogram was then constructed based on these factors. The diagnostic performance of the nomogram was evaluated using the area under the receiver operating characteristic curve (AUROC) and a calibration plot. The clinical usefulness of the nomogram was estimated using decision curve analysis (DCA). Results: Among the 369 patients undergoing gastrointestinal tumor resection, 79 patients had POCD, with a positive rate of 21.4%. The nomogram model comprised the following variables: age, body mass index (BMI), history of cerebrovascular disease, preoperative white blood cell (WBC) count, preoperative hemoglobin (Hb) level, intra-operative blood loss, and operation time. The model showed good discrimination, with an area under the curve (AUC) of 0.710 (95% CI = 0.645-0.775), and good calibration (Hosmer-Lemeshow test, χ Conclusion: This scoring system is the first nomogram model developed for the prediction of POCD in elderly patients undergoing gastrointestinal tumor resection. It has good efficacy in the prediction of POCD risk and could provide an important reference for the prevention, management, and treatment of POCD.
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