Evidence map›Paper›PMID 36388925›Full record

ArticleFrontiers in medicine2022

Potential lipid-lowering effects of

Ye Li Lee, Sang Yeoup Lee

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03773315 (Effect of Ulmus Macrocarpa Hance Extract on Lipid Profile in Adults With Dyslipidemia), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03773315 nacompletednot on this map

Effect of Ulmus Macrocarpa Hance Extract on Lipid Profile in Adults With Dyslipidemia: a RCT

TypeinterventionalSponsorSang Yeoup LeeRan2018 to 2020Enrolled80ConditionsDyslipidemiasArmsUMH extract, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ye Li LeeIntegrated Research Institute for Natural Ingredients and Functional Foods, Yangsan, South Korea.
Sang Yeoup LeeIntegrated Research Institute for Natural Ingredients and Functional Foods, Yangsan, South Korea.
Pusan National University Yangsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Materials and methods: In the current double-blind placebo-controlled randomized clinical trial, 80 patients with untreated high LDL-C concentrations (130-190 mg/dl) were randomly allocated to either the "UME group" (received 500 mg UME as two capsules per day) or the "Placebo group" (received placebo containing cornstarch as two capsules per day) for 12 weeks. The primary outcome was the change in LDL-C concentration within the 12-week treatment period; secondary outcomes included changes in total cholesterol (TC), triglyceride, high-density lipoprotein cholesterol, apolipoprotein A1, and apolipoprotein B (ApoB) concentrations. Results: UME over 12 weeks led to a greater decrease in LDL-C, TC, and ApoB concentrations than did the placebo as follows: by 18.1 mg/dl ( Discussion: UME causes a significant improvement in lipid profiles in adults with untreated high LDL-C concentrations. Clinical trial registration: [www.clinicaltrials.gov/], identifier [NCT03773315].

Indexed as

dietary supplementsdyslipidemialipidslipoproteinrandomized controlled trialUlmus macrocarpa Hance

Identifiers

PMID36388925
PMCPMC9663492
OpenAlexW4308008167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.