Evidence map›Paper›PMID 36388753›Full record

ArticleGynecologic oncology reports2022

Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer - A case report.

Luiza Chepkemoi, Oluwaseyi Ajayi, Nancy Anabaraonye, Onyinye D Balogun

Open access · goldAbstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Luiza ChepkemoiFrank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT 06473, United States.
Oluwaseyi AjayiUniversity of Maryland, College Park, MD 20742, United States.
Nancy AnabaraonyeUniversity of Pennsylvania, Philadelphia, PA 19104, United States.
Onyinye D BalogunWeill Cornell Medicine/New York Presbyterian Hospital, New York, NY 10065, United States.
Cornell University · USQuinnipiac University · USUniversity of Maryland, College Park · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer, also known as uterine cancer, is the second most common cancer affecting women globally and the fourth most prevalent in the United States (US). Treatment often involves a combination of surgery, radiotherapy and chemotherapy depending on the severity. In this case report, we present two patients with relapsed endometrial carcinomas, who responded positively to combined radiotherapy and immunotherapy followed by maintenance immunotherapy. Given the worsening prognoses associated with recurrent endometrial cancers, these two cases warrant the further exploration of the concurrent administration of immunotherapy and radiation therapy in the context of clinical trials.

Indexed as

Case reportCK7, Cytokeratin 7Concurrent radiotherapy and immunotherapyCT, Computed TomographyCTLA-4-Cyctotoxic T, Lymphocyte Associated Protein 4Endometrial cancerFDG, FluorodeoxyglucoseGLOBOCAN, Global Cancer ObservatoryImmunotherapyPAX8, Paired Box Gene 9PET, Positron Emission TomographyPTEN, Phosphate and Tensin HomologRadiotherapySUV, Standardized Uptake Value

Identifiers

PMID36388753
PMCPMC9647195
OpenAlexW4307153210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.