ArticleTherapeutic advances in ophthalmology
Choroidal thickness in patients with systemic arterial hypertension: a systematic review and meta-analysis.
Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 17 citations in OpenAlex.
- Short-Term Effect of Stimulating the Pterygopalatine Ganglion Via Electroacupuncture on Choroidal Structure in Human Subjects.Translational vision science & technology · 2024Trial
- Investigating Retinal Microvascular Changes Using OCT-Angiography: The Role of Oxidative Stress and Endothelial Dysfunction in Hypertensive Nephropathy.Medicina (Kaunas, Lithuania) · 2026Article
- Retinal and Choroidal Metrics Are Dynamic Markers of the Maternal Vascular Response to Pregnancy.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Choroidal microcirculation in pediatric craniopharyngioma: postoperative alterations in choroidal thickness.Frontiers in pediatrics · 2026Article
- Retinal and Choroidal Alterations in Heart Failure: A Systematic Review and Meta-analysis of OCT and OCT-A Findings with Emphasis on HFrEF.Ophthalmology and therapy · 2025Review
- Macular Choroidal Thickness in Keratoconus: Systematic Review and Meta-Analysis of Current Evidence.Diagnostics (Basel, Switzerland) · 2025Review
- Comparison of AI-Automated and Manual Subfoveal Choroidal Thickness Measurements in an Elderly Population Using Optical Coherence Tomography.Translational vision science & technology · 2025Article
- Relationship between choroidal structure and myocardial collateral flow regulation in acute and chronic coronary heart disease.International ophthalmology · 2025Observational
- Choroidal thickness as predictor of subclinical carotid atherosclerosis in adults with type 1 diabetes.Scientific reports · 2025Article
- A Pilot Study Investigating the Relationship Between Choroidal Thickness and Choroidal Vascular Index and Coronary Artery Ectasia.Diagnostics (Basel, Switzerland) · 2025Article
- Causal Effects Between Retinal Characteristics and Cardiovascular Diseases: Insights from Genetic Correlation, Mendelian Randomization, and Cross-Sectional Study.Global heart · 2025Article
- Oculomics meets exposomics: a roadmap for applying multi-modal ocular biomarkers in precision environmental health research.Exposome · 2025Review
- Ocular Biometry Profile and Its Associations with Systemic and Demographic Factors in Thai Cataract Patients.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Exploration of Choroidal Thinning Located Temporal to the Fovea: A Pilot Study.Journal of clinical medicine · 2024Article
- Looking into the Eyes to See the Heart of Chronic Kidney Disease Patients.Life (Basel, Switzerland) · 2024Article
- Retinal Structural and Vascular Changes in Patients with Coronary Artery Disease: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Choroidal Changes in Patients with Diabetic Retinopathy: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2024Article
- Automatic fovea detection and choroid segmentation for choroidal thickness assessment in optical coherence tomography.International journal of ophthalmology · 2024Article
- Evaluation of Tropicamide-Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The global burden of hypertension is constantly increasing with adverse cardiovascular and ocular sequelae. The association between elevated blood pressure and choroidal thickness (CT), as assessed via optical coherence tomography (OCT), is poorly understood. Objectives and Design: Studies including hypertensive adults and normotensive controls undergoing OCT were evaluated for inclusion in this meta-analysis. The primary endpoint was CT difference between hypertensive and normotensive adults. Data Sources and Methods: We conducted a systematic review and after searching 1011 results from MEDLINE, ClinicalTrials.gov, medRxiv and Cochrane Library, six studies were deemed eligible and were pooled according to a random-effect model. Results: A statistically significant reduction in choroidal thickness was found in hypertensive adults ( Conclusion: Choroidal thickness is reduced among hypertensive subjects compared with normotensive controls. This finding mandates further examination in the context of long-term clinical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.