Evidence map›Paper›PMID 36388416›Full record

ArticleNeuro-oncology practice2022

Introducing FCR6-Brain: Measuring fear of cancer recurrence in brain tumor patients and their caregivers.

Sarah Ellen Braun, Kelcie D Willis, Samantha N Mladen, Farah Aslanzadeh, Autumn Lanoye, Jenna Langbein, Morgan Reid, Ashlee R Loughan

Open access · greenAbstract read
In one paragraph

Article in Neuro-oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trajectories of dyadic fear of cancer recurrence in breast cancer couples: a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  2. Neuro-oncology practice · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. The impact of a primary brain tumor diagnosis on caregivers: Insights from the patients' perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sarah Ellen BraunDepartment of Neurology, Virginia Commonwealth University, 1201 East Marshall St, Richmond, VA, USA.ORCID https://orcid.org/0000-0002-7184-0125
Kelcie D WillisDepartment of Psychology, Virginia Commonwealth University, 806 West Franklin Street, Box 842018, Richmond, VA 23284-2018, USA.
Samantha N MladenDepartment of Psychology, Virginia Commonwealth University, 806 West Franklin Street, Box 842018, Richmond, VA 23284-2018, USA.
Farah AslanzadehDepartment of Neuropsychology, Baltimore VA Medical Center, 10 N Greene St, Baltimore, MD 21201, USA.
Autumn LanoyeMassey Cancer Center, Virginia Commonwealth University, 401 College Street Richmond, VA, USA.
Jenna LangbeinVirginia Commonwealth University School of Medicine, 1201 E Marshall St #4-100, Richmond, VA 23298, USA.
Morgan ReidDepartment of Psychology, Virginia Commonwealth University, 806 West Franklin Street, Box 842018, Richmond, VA 23284-2018, USA.
Ashlee R LoughanDepartment of Neurology, Virginia Commonwealth University, 1201 East Marshall St, Richmond, VA, USA.
Virginia Commonwealth University · USBaltimore VA Medical Center · US

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

Background: Fear of cancer recurrence (FCR) is a psychological consequence of cancer diagnosis that impacts quality of life in neuro-oncology. However, the instruments used to assess FCR have not been tested for validity in patients with brain tumors. The present study explored the psychometric properties of a brief FCR scale in patients with primary brain tumor (PBT) and their caregivers. Methods: Adult patients with PBT ( Results: EFAs revealed a single factor with one item demonstrating poor loading for both patients and caregivers. Removal of the item measuring hypervigilance symptoms (checking for physical signs of tumor) greatly improved the single factor metrics. The amended scale (FCR6-Brain) demonstrated good convergent validity. Caregiver FCR was significantly higher than patient. Clinical guidance to identify clinically significant FCR was introduced. Age, gender, and time since diagnosis were related to FCR, with higher FCR in younger women more recently diagnosed. Conclusions: The FCR6-Brain is the first validated instrument to assess FCR in this population and should be used to identify individuals at risk for FCR and guide development of future psychotherapeutic interventions. This study highlights the distinct characteristics of FCR in neuro-oncology. Symptoms of hypervigilance in PBT patients need further investigation.

Indexed as

caregiversfear of cancer recurrencemeasurement validityneuro-oncologyprimary brain tumor

Identifiers

PMID36388416
PMCPMC9665059
OpenAlexW4281643598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.