ArticleFrontiers in public health2022
Landscape and predictions of inflammatory bowel disease in China: China will enter the Compounding Prevalence stage around 2030.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Global, Regional and National Estimates of Hip Fracture Burden Associated with Type 2 Diabetes in Adults Aged Over 40 from 1990 to 2021 and Projections to 2046.Calcified tissue international · 2025Pooled it
- Phenotypic switching of gastrointestinal smooth muscle cells and the regulatory role of macrophages: a literature review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- Disease burden of inflammatory bowel disease and subtypes in older adults in 172 high- and middle-income countries: Trends from 2000 to 2023 and projections to 2040.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Inflammatory bowel disease burden in China and the United States from 1990-2023 and prediction to 2050.Internal and emergency medicine · 2026Article
- Article
- Relationship between the appendix and ulcerative colitis: A new discovery.World journal of gastrointestinal endoscopy · 2026Review
- Canonical pathways and selective mechanisms of autophagy in inflammatory bowel disease.Advanced biotechnology · 2026Review
- Recombinant BMP9 Reinforces Gut Vascular Barrier in Experimental Colitis.Biomedicines · 2026Article
- Review
- Challenges in dietary decision-making among Chinese adults with inflammatory bowel disease: a qualitative study.BMJ open · 2025Article
- Inflammatory bowel disease in paediatrics: Navigating the old challenges and emerging frontiers.World journal of gastroenterology · 2025Review
- Multidimensional fatigue mediates the relationship between sexual quality of life and perceived stress in patients with inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- Association of vitamin D and platelet-to-lymphocyte ratio in treatment escalation risk for newly diagnosed Crohn's disease adults.Nutrition journal · 2025Article
- Management of Fatigue in Inflammatory Bowel Disease: A Narrative Review.International journal of general medicine · 2025Review
- Comprehensive analysis of anoikis-related gene signature in ulcerative colitis using machine learning algorithms.Frontiers in medicine · 2025Article
- Histone deacetylase in inflammatory bowel disease: novel insights.Therapeutic advances in gastroenterology · 2025Review
- CircHIPK2 Contributes Cell Growth in Intestinal Epithelial of Colitis and Colorectal Cancer through Promoting TAZ Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Application of Dynamic Contrast-Enhanced Ultrasound in Evaluation the Activity of Crohn's Disease.Diagnostics (Basel, Switzerland) · 2024Article
- The new insights of hyperbaric oxygen therapy: focus on inflammatory bowel disease.Precision clinical medicine · 2024Review
- Global Burden of Inflammatory Bowel Disease Among Children and Adolescents: A Comprehensive Analysis (1990-2019).International journal of public health · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aims to explore the epidemiological trends of inflammatory bowel disease (IBD) over the past three decades in China and further predict the trends of IBD in the next 25 years. Methods: The prevalence, incidence, mortality, years of life lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life years (DALYs), and annual percentage changes of the above metrics of IBD in China from 1990 to 2019 were extracted from the Global Burden of Disease Study 2019. The corresponding trends in the next 25 years were predicted. Results: From 1990 to 2019, the cases of IBD in China raised to 484 thousand [95% uncertainty interval (UI) 411-571] and 427 thousand (366-498) among males and females, respectively. The age-standardized incidence rate of IBD increased from 1.72 per 100,000 population (1.44-2.05) to 3.35 per 100,000 population (2.88-3.88) among males and from 1.20 per 100,000 population (1.02-1.42) to 2.65 per 100,000 population (2.29-3.08) among females. The highest incidence rate occurred in people aged 35-39 years. The total YLDs attributed to IBD significantly increased, but the YLLs showed a decreasing trend, resulting in minor alterations of the DALYs. In the next 25 years, the incidence of IBD would continue to increase until a plateau by 2030, and IBD-related deaths would also increase to about 7.57 thousand by 2044 despite the decreasing age-standardized mortality rate. Similar trends were observed for both sexes, with a slight male predominance. Conclusions: Although China is still a low-endemic area of IBD, the prevalence and incidence of IBD dramatically increased in the past three decades. The burden of IBD in China is expected to grow continuously in the next 25 years due to the large population base and severe aging problem. China is estimated to enter the Compounding Prevalence stage around 2030.
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