Evidence map›Paper›PMID 36388191›Full record

ArticleFrontiers in neurology2022

Integrin subunit alpha V is a potent prognostic biomarker associated with immune infiltration in lower-grade glioma.

Zilong Tan, Zhe Zhang, Kai Yu, Huan Yang, Huaizhen Liang, Tianzhu Lu, Yulong Ji, Junjun Chen, Wei He, Zhen Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Correlation ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Zilong TanDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhe ZhangDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Kai YuDepartment of Neurosurgery, People's Hospital of Wuhan University, Wuhan, China.
Huan YangDepartment of Neurosurgery, Changde Hospital of Traditional Chinese Medicine, Changde, China.
Huaizhen LiangDepartment of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tianzhu LuDepartment of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, China.
Yulong JiJiangxi Key Laboratory of Translational Cancer Research, Jiangxi Cancer Hospital of Nanchang University, Nanchang, China.
Junjun ChenJiangxi Key Laboratory of Translational Cancer Research, Jiangxi Cancer Hospital of Nanchang University, Nanchang, China.
Wei HeDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhen ChenDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Yuran MeiDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xiao-Li ShenDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CNHuazhong University of Science and Technology · CNJiangxi Provincial Cancer Hospital · CNThe First People's Hospital of Changde · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a member of integrin receptor family, ITGAV (integrin subunit α V) is involved in a variety of cell biological processes and overexpressed in various cancers, which may be a potential prognostic factor. However, its prognostic value and potential function in lower-grade glioma (LGG) are still unclear, and in terms of immune infiltration, it has not been fully elucidated. Here, the expression preference, prognostic value, and clinical traits of ITGAV were investigated using The Cancer Genome Atlas database (

Indexed as

biological functionbiomarkerintegrin subunit alpha Vlow grade gliomaprognosis

Identifiers

PMID36388191
PMCPMC9642104
OpenAlexW4307373786

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.