Evidence map›Paper›PMID 36388115›Full record

ArticleFrontiers in physiology2022

An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.

Charles Colin Thomas Hindmarch, Lian Tian, Ping Yu Xiong, Francois Potus, Rachel Emily Teresa Bentley, Ruaa Al-Qazazi, Kurt W Prins, Stephen L Archer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Multi-omic and multispecies analysis of right ventricular dysfunction.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  6. Article
  7. Article
  8. More than just a small left ventricle: the right ventricular fibroblast and ECM in health and disease.American journal of physiology. Heart and circulatory physiology · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Charles Colin Thomas HindmarchQCPU, Queen's Cardiopulmonary Unit, Translational Institute of Medicine (TIME), Department of Medicine, Queen's University, Kingston, ON, Canada.
Lian TianDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Ping Yu XiongDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Francois PotusPulmonary Hypertension Research Group, Centre de Recherche de l'Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, QC, Canada.
Rachel Emily Teresa BentleyDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Ruaa Al-QazaziDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Kurt W PrinsCardiovascular Division, Lillehei Heart Institute, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Stephen L ArcherQCPU, Queen's Cardiopulmonary Unit, Translational Institute of Medicine (TIME), Department of Medicine, Queen's University, Kingston, ON, Canada.
Queen's University · CAInstitut Universitaire de Cardiologie et de Pneumologie de Québec · CAUniversity of Minnesota · US

Funding

GP130 Antagonism in Porcine RV Pressure OverloadR01HL162927 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$3.3M
Multi-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule InteractionsR01HL158795 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$2.8M
Mechanisms of Junctophilin-2 Misregulation that contribute to right ventricular dysfunction in pulmonary arterial hypertensionK08HL140100 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRINS, KURT W · 2018 to 2022
$785k
NHLBI NIH HHS K08 HL140100NHLBI NIH HHS R01 HL158795NHLBI NIH HHS R01 HL162927
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

glutathione S-transferase zeta 1 (Gstz1)heme oxygenase 1 (HMOX1)mitochondriaperiostin (POSTN)S100 calcium-binding protein A4 (S100A4)SU5416-chronic hypoxia PAH modeltenascin-C (TNC)thrombospondin-4 (Thbs4)

Identifiers

PMID36388115
PMCPMC9664166
OpenAlexW4307762010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.