Evidence map›Paper›PMID 36387945›Full record

ArticleNeuropsychiatric disease and treatment2022

Depression, Diabetes Mellitus and Mortality in Older Adults: A National Cohort Study in Taiwan.

Vincent Chin-Hung Chen, Tsu-Nai Wang, Ming-Chia Hsieh, Shih-Yong Chou, Meng-Chih Lee, Roger S McIntyre, Mong-Liang Lu, Yin-To Liao, Chih-Jung Yeh

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Vincent Chin-Hung ChenDepartment of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Tsu-Nai WangDepartment of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ming-Chia HsiehU Come Joint Clinic, Taichung, Taiwan.
Shih-Yong ChouDepartment of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Meng-Chih LeeDepartment of Family Medicine, Taichung Hospital, Taichung, Taiwan.
Roger S McIntyreUniversity of Toronto, Toronto, ON, Canada.
Mong-Liang LuDepartment of Psychiatry, Wan-Fang Hospital and School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Yin-To LiaoDepartment of Psychiatry, Chung Shan Medical University Hospital, Taichung, Taiwan.ORCID 0000-0002-3143-3672
Chih-Jung YehInstitute of Population Health Sciences, National Health Research Institutes, Taipei, Taiwan.ORCID 0000-0002-1179-1616
Chang Gung University · TWChaoyang University of Technology · TWChiayi Chang Gung Memorial Hospital · TWChung Shan Medical University Hospital · TWKaohsiung Medical University · TWNational Health Research Institutes · TWUniversity of Toronto · CAWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Diabetes mellitus (DM) increases the risk of cardiovascular and all-cause mortality. The coexistence of depression and DM is associated with an increased risk of DM complications and functional morbidity. The independent effect of depression on mortality in patients with DM is unclear, and relevant Asian studies have provided inconsistent results. Accordingly, this study assessed the independent and additive effects of DM and depression on mortality in a nationally representative cohort of older adults in Taiwan over a 10-year observation period. Patients and Methods: A total of 5041 participants aged 50 years or older were observed between 1996 and 2007. We defined depression as a score of ≥8 on the 10-item Center for Epidemiologic Studies Depression (CES-D 10) scale. Additionally, we defined participants as having type 2 DM if they had received a diagnosis of type 2 DM from a health-care provider. Cox proportional hazard models were applied to analyze predictors of mortality in depression and DM comorbidity groups. Results: During the 10-year follow-up period, 1637 deaths were documented. After adjustment for potential confounders, the hazard ratios for mortality in participants with both depression and DM, DM only, and depression only were 2.47 (95% confidence interval [CI]: 2.02-3.03), 1.95 (95% CI: 1.63-2.32), and 1.23 (95% CI: 1.09-1.39), respectively. Conclusion: The co-occurrence of depression with DM in Asian adults increased overall mortality rates. Our results indicate that the increased mortality hazard in individuals with DM and depression was independent of sex.

Indexed as

cohortdepressiondiabetes mellitusmortality

Identifiers

PMID36387945
PMCPMC9662019
OpenAlexW4308623214

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.