Evidence map›Paper›PMID 36387839›Full record

ArticleJournal of asthma and allergy2022

Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study.

Johanna Heldin, Andrei Malinovschi, Ane Johannessen, Kjell Alving, Mathias Holm, Karl A Franklin, Bertil Forsberg, Vivi Schlünssen, Rain Jögi, Thorarinn Gislason and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
  6. Article
  7. Allergic rhinitis: Incidence and remission from childhood to young adulthood-A prospective study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Johanna HeldinDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Andrei MalinovschiDepartment of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4098-7765
Ane JohannessenCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0003-3269-8354
Kjell AlvingDepartment of Women's and Children's Health, Paediatric Research, Uppsala University, Uppsala, Sweden.
Mathias HolmOccupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Karl A FranklinDepartment of Surgical and Perioperative Sciences, Surgery, Umeå University, Umeå, Sweden.ORCID 0000-0002-5306-1697
Bertil ForsbergDepartment of Public Health and Clinical Medicine, Section of Sustainable Health, Umeå University, Umeå, Sweden.
Vivi SchlünssenDepartment of Public Health, Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-4915-1734
Rain JögiTartu University Hospital, Lung Clinic, Tartu, Estonia.
Thorarinn GislasonThe Medical Faculty, University of Iceland, Reykjavik, Iceland.
Bryndis BenediktsdottirThe Medical Faculty, University of Iceland, Reykjavik, Iceland.
Cecilie SvanesCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0001-8512-5192
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5093-6980
Uppsala University · SEReykjavík University · ISUmeå University · SEAarhus University · DKHaukeland University Hospital · NOTartu University Hospital · EEUniversity of Bergen · NOUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis. Methods: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989-1992) and two follow-ups (RHINE II, 1999-2001 and RHINE III, 2010-2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III. Results: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22-4.85)) and living in an apartment (1.45 (1.06-1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51-0.90)), asthma onset ≤ 12 years of age (0.49 (0.35-0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47-0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age ≥ 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant. Conclusion: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis.

Indexed as

allergic rhinitisasthmaepidemiologyremission

Identifiers

PMID36387839
PMCPMC9643071
OpenAlexW4308074155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.