ArticleWorld journal of clinical cases2022
Relationship between lipids and sleep apnea: Mendelian randomization analysis.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 1 citations in OpenAlex.
- Blood lipid profile, HbA1c, fasting glucose, and diabetes: a cohort study and a two-sample Mendelian randomization analysis.Journal of endocrinological investigation · 2024Article
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2 authors at 1 institution in 1 country.
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Abstract
backgroundLipids increase the risk of sleep apnea; however, the causality between them is still inconclusive.
aimTo explore the causal relationship between serum lipids and sleep apnea using two-sample Mendelian randomization (MR) analysis.
methodsSingle nucleotide polymorphism (SNP) data related to serum lipids were obtained from the Global Lipids Genetics Consortium study, which included 188578 individuals of European ancestry. Additionally, sleep apnea-related SNP data were collected from the United Kingdom Biobank study, which comprised 463005 individuals of European ancestry. Two-sample MR analysis was performed to assess the causality between serum lipids and sleep apnea based on the above public data.
resultsGenetically predicted low-density lipoprotein (odds ratio [OR] = 0.99, 95% confidence interval [CI] = 0.99 to 1.00;
conclusionOur MR analysis suggests that genetically predicted serum lipids are not risk factors of sleep apnea.
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