Evidence map›Paper›PMID 36387789›Full record

ReviewWorld journal of clinical cases2022

Diabetes and skin cancers: Risk factors, molecular mechanisms and impact on prognosis.

Elena-Codruta Dobrică, Madalina Laura Banciu, Vincent Kipkorir, Mohammad Amin Khazeei Tabari, Madeleine Jemima Cox, L V Simhachalam Kutikuppala, Mihnea-Alexandru Găman

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 6 countries.

Elena-Codruta DobricăDoctoral School, University of Medicine and Pharmacy of Craiova, Craiova 200349, Romania.
Madalina Laura BanciuDepartment of Dermatology, "Elias" University Emergency Hospital, Bucharest 011461, Romania.
Vincent KipkorirDepartment of Human Anatomy, University of Nairobi, College of Health Sciences, Nairobi 00100, Kenya.
Mohammad Amin Khazeei TabariUSERN Office, Mazandaran University of Medical Sciences, Sari 48175-866, Iran.
Madeleine Jemima CoxUniversity of New South Wales, University of New South Wales, Sydney 2052, Australia.
L V Simhachalam KutikuppalaDr NTR University of Health Sciences, Vijayawada, Andhra Pradesh 520008, India.
Mihnea-Alexandru GămanFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania. mihneagaman@yahoo.com.
Carol Davila University of Medicine and Pharmacy · RODr. NTR University of Health Sciences · INEmergency University · USMazandaran University of Medical Sciences · IRUniversity of Medicine and Pharmacy of Craiova · ROUniversity of Nairobi · KEUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes and skin cancers have emerged as threats to public health worldwide. However, their association has been less intensively studied. In this narrative review, we explore the common risk factors, molecular mechanisms, and prognosis of the association between cutaneous malignancies and diabetes. Hyperglycemia, oxidative stress, low-grade chronic inflammation, genetic, lifestyle, and environmental factors partially explain the crosstalk between skin cancers and this metabolic disorder. In addition, diabetes and its related complications may interfere with the appropriate management of cutaneous malignancies. Antidiabetic medication seems to exert an antineoplastic effect, however, future large, observation studies with a prospective design are needed to clarify its impact on the risk of malignancy in diabetes. Screening for diabetes in skin cancers, as well as close follow-up for the development of cutaneous malignancies in subjects suffering from diabetes, is warranted.

Indexed as

Basocellular carcicomaDiabetesMelanomaSkin cancersSquamous cell carcinoma

Identifiers

PMID36387789
PMCPMC9649529
OpenAlexW4307560278

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.