Evidence map›Paper›PMID 36387579›Full record

ArticleHeliyon2022

Erliang Li, Rongbao Yan, Kang Yan, Ruqin Huang, Rui Zhang, Yanhua Wen, Shuang Li, Peng Li, Qiong Ma, Bo Liao

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Erliang LiDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Rongbao YanDepartment of Orthopaedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Kang YanDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Ruqin HuangDepartment of Traditional Chinese Medicine, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Rui ZhangDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Yanhua WenDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Shuang LiDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Peng LiDepartment of Basic Science, Shanxi Agricultural University, Taigu, 030801, Shanxi, China.
Qiong MaDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Bo LiaoDepartment of Orthopedics, Tangdu Hospital, Air Force Military Medical University, Xi'an 710038, Shaanxi, China.
Harbin Medical University · CNShanxi Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Spinal cord injury (SCI) often leads to severe physiological and pathological changes in patients. Erxian Decoction (EXD) is effective in the postoperative treatment of spinal cord injury, but its specific mechanism of action is poorly defined. Methods: Network pharmacology and molecular docking were used to predict the potential mechanisms of EXD in SCI. Results: Conclusions: EXD inhibits apoptosis by activating Akt1, reduce spinal cord edema and restore behavioral function after SCI in rats.

Indexed as

Akt1ApoptosisSpinal cord injury

Identifiers

PMID36387579
PMCPMC9641199
OpenAlexW4308036924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.