ArticleHeliyon2022
Characterizing optimum electrospinning conditions for graft urethanized Poly(Vinyl Alcohol)(U-PVA).
Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- Development and Formulation of Nanofiber-Based Ophthalmic Inserts for the Treatment of Fungal Keratitis.Pharmaceutics · 2026Article
- Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine.Nanomaterials (Basel, Switzerland) · 2025Review
- Chemoresistive Gas Sensors Based on Electrospun 1D Nanostructures: Synergizing Morphology and Performance Optimization.Sensors (Basel, Switzerland) · 2024Review
- The effect of using two stabilization temperatures and fixation process on preparation of carbon nanofibers.Heliyon · 2024Article
- Recent progress of electrospun nanofibers as burning dressings.RSC advances · 2024Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poly(vinyl alcohol) (PVA) is a water-soluble polymer that has been widely used in medical and pharmaceutical applications. For this study, we grafted urea to PVA to enhance its wettability and solubility in water. We used a scanning electron microscope (SEM) to characterize the electrospun graft urethanized poly(vinyl alcohol) U-PVA and determine the best electrospinning conditions. The capillary-collector distance, applied voltage, and flow rate all had notable effects on fiber diameter and morphology. When we increased the capillary-collector distance to 20 cm and set the applied voltage to 25 kV, the fiber diameter and bead formation decreased, while decreasing the flow rate to 1 mL/h resulted in a homogeneous fibrous structure with an average fiber diameter equal to 159 ± 59.3 nm. We compared the wettabilities, Fourier transform infra-red FTIR spectra and insulin drug release of graft U-PVA and pure PVA electrospun specimens. Grafting urea to PVA enhanced its wettability, and drug release rate with time; indicating the effectiveness of graft U-PVA as a drug delivery system with high drug-release rates.
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Registered trials
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