ArticleHeliyon2022
Curcumin coated 3D biocomposite scaffolds based on chitosan and cellulose for diabetic wound healing.
Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Chitosan-Nanoencapsulated Curcumin for the Treatment of Diabetic Foot Ulcers: A Review.Polymers · 2026Review
- Synergistic integration of exosomes and natural compounds in 3D-printed bioscaffolds: Revolutionizing diabetic wound healing through multifunctional therapeutic platforms.Iranian journal of basic medical sciences · 2026Review
- Targeting diabetic foot ulcer pathophysiology: altered signaling pathways and 3D scaffold as an emerging treatment strategy.3 Biotech · 2025Review
- Biocompatible nanostructured chitosan scaffolds for enhanced diabetic wound healing: Innovations and strategies.3 Biotech · 2025Review
- Herbal bioactive-loaded biopolymeric formulations for wound healing applications.RSC advances · 2025Review
- Article
- Article
- Improvement of Chitosan Films Properties by Blending with Cellulose, Honey and Curcumin.Polymers · 2023Article
- Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine.Frontiers in bioengineering and biotechnology · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of present work is to fabricate porous three-dimensional biocomposite scaffolds with interconnected pore networks and mechanical strength for wound healing. Variable concentrations of chitosan and methylcellulose hydrogels were blended in the presence of calcium cations to prepare scaffolds by freeze-drying method. Curcumin-aerosol was deposited over the scaffold surface to improve antimicrobial efficacy. Scaffold stability and curcumin interaction were evaluated by Differential Scanning Calorimeter, Thermal Gravimetric Analyzer and Fourier Transform Infrared Spectrophotometer. Scanning Electron Microscopy indicate multi-layered porosity, mesh-like structure and pore-size ranging from 50 to 500 μm. Erythrocyte interaction with chitosan and methylcellulose using Surface Plasmon Resonance assay in the presence of curcumin depicted high binding affinity of chitosan alone than curcumin. The antibacterial activity of SCF-4C against
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.