Evidence map›Paper›PMID 36387198›Full record

ReviewFrontiers in oncology2022

Super-enhancers in esophageal carcinoma: Transcriptional addictions and therapeutic strategies.

Yang Shi, Meiqi Wang, Dan Liu, Saif Ullah, Xing Ma, Huiyu Yang, Bingrong Liu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Enhancer regulation in cancer: from epigenetics to mArchives of pharmacal research · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yang ShiDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Meiqi WangAcademy of Medical Sciences Zhengzhou University, Zhengzhou, China.
Dan LiuDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Saif UllahDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xing MaDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Huiyu YangDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Bingrong LiuDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhengzhou University · CNFirst Affiliated Hospital of Zhengzhou University · CNHenan Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumorigenesis of esophageal carcinoma arises from transcriptional dysregulation would become exceptionally dependent on specific regulators of gene expression, which could be preferentially attributed to the larger non-coding

Indexed as

core regulatory circuitryesophageal carcinomahistone acetylationsuper-enhancerstranscriptional dependence

Identifiers

PMID36387198
PMCPMC9647064
OpenAlexW4307632185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.