Evidence map›Paper›PMID 36387151›Full record

ReviewFrontiers in oncology2022

HPV vaccination in Latin America: Coverage status, implementation challenges and strategies to overcome it.

Angélica Nogueira-Rodrigues, Matheus Gonçalves Flores, Avelar Oliveira Macedo Neto, Lucélia Antunes Coutinho Braga, Carolina Martins Vieira, Renata Maria de Sousa-Lima, Diocésio Alves Pinto de Andrade, Karime Kalil Machado, Andrea Paiva Gadelha Guimarães

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Review
  3. Determinants of HPV vaccine hesitancy in South Asia: a systematic review.Clinical and experimental vaccine research · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Barriers in the prevention and early detection of human papillomavirus in Latin America.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  13. Global disparities in gynecologic cancer outcomes: A call for action.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angélica Nogueira-RodriguesDepartment of Internal Medicine, Federal University of Minas Gerais, Belo Horizontel, Brazil.
Matheus Gonçalves FloresFederal University of Minas Gerais, Belo Horizontel, Brazil.
Avelar Oliveira Macedo NetoFederal University of Minas Gerais, Belo Horizontel, Brazil.
Lucélia Antunes Coutinho BragaFundação Oswaldo Cruz (FIOCRUZ) Minas, Belo Horizontel, Brazil.
Carolina Martins VieiraClinical Oncologist at Oncoclinicas, Belo Horizontel, Brazil.
Renata Maria de Sousa-LimaClinical Oncologist at Oncoclinicas, Belo Horizontel, Brazil.
Diocésio Alves Pinto de AndradeBrazilian Gynecologic Oncology Group, EVA, São Paulo, Brazil.
Karime Kalil MachadoBrazilian Gynecologic Oncology Group, EVA, São Paulo, Brazil.
Andrea Paiva Gadelha GuimarãesBrazilian Gynecologic Oncology Group, EVA, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer remains a leading cause of morbidity and mortality amongst females in Latin America (LATAM). Cervical cancer is a preventable disease and HPV vaccination is a main key strategy towards its elimination. This study analyzes HPV vaccine implementation current status and the main barriers to achieve adequate coverage in the region. Data from the nineteen sovereign states of LATAM (comprised of all Portuguese and Spanish-speaking nations located south of the United States) were collected, including year of HPV vaccine implementation, gender and age targets, the number of doses included in the public program and coverage by dose. Sixteen out of the 19 evaluated countries have already implemented HPV vaccination programs. However, despite its proven efficacy and safety, HPV vaccine uptake in LATAM has been lower than expected. There is an evident decline in adhesion, mainly regarding the second dose. Several reasons are probably involved, of note: limited knowledge of HPV and HPV vaccine, misguided safety concerns, high cost, cultural barriers, and the Covid19 pandemic. Proper strategies to overcome these barriers are needed to ensure successful uptake. Effective policies are: adopting the one dose schedule, delivering the vaccine on both health center and schools, and advising health professionals to recommend the vaccine. Further research regarding HPV vaccine hesitancy in Latin America is needed.

Indexed as

cervical cancercoverageHPVimplementationLatin Americavaccine

Identifiers

PMID36387151
PMCPMC9645205

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.