Evidence map›Paper›PMID 36387121›Full record

ArticleFrontiers in oncology2022

An exploratory study of CT radiomics using differential network feature selection for WHO/ISUP grading and progression-free survival prediction of clear cell renal cell carcinoma.

Fu Yin, Haijie Zhang, Anqi Qi, Zexuan Zhu, Liyang Yang, Ge Wen, Weixin Xie

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fu YinCollege of Electronics and Information Engineering, Shenzhen University, Shenzhen, China.
Haijie ZhangMedical Imaging Department, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Anqi QiMedical Imaging Department, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zexuan ZhuCollege of Computer Science and Software Engineering, Shenzhen University, Shenzhen, China.
Liyang YangMedical Imaging Department, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ge WenMedical Imaging Department, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Weixin XieCollege of Electronics and Information Engineering, Shenzhen University, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the feasibility of predicting the World Health Organization/International Society of Urological Pathology (WHO/ISUP) grade and progression-free survival (PFS) of clear cell renal cell cancer (ccRCC) using the radiomics features (RFs) based on the differential network feature selection (FS) method using the maximum-entropy probability model (MEPM). Methods: 175 ccRCC patients were divided into a training set (125) and a test set (50). The non-contrast phase (NCP), cortico-medullary phase, nephrographic phase, excretory phase phases, and all-phase WHO/ISUP grade prediction models were constructed based on a new differential network FS method using the MEPM. The diagnostic performance of the best phase model was compared with the other state-of-the-art machine learning models and the clinical models. The RFs of the best phase model were used for survival analysis and visualized using risk scores and nomograms. The performance of the above models was tested in both cross-validated and independent validation and checked by the Hosmer-Lemeshow test. Results: The NCP RFs model was the best phase model, with an AUC of 0.89 in the test set, and performed superior to other machine learning models and the clinical models (all Conclusion: The NCP CT-based RFs selected by differential network FS could predict the WHO/ISUP grade and PFS of RCC.

Indexed as

clear cell renal carcinomadifferential network feature selectionprogression-free survivalradiomics featuresWHO/ISUP grade

Identifiers

PMID36387121
PMCPMC9648858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.